{"id":7715,"date":"2025-07-01T19:51:48","date_gmt":"2025-07-01T11:51:48","guid":{"rendered":"https:\/\/allcancer.com\/cancer\/myelodysplastic-syndromes-mds-2\/"},"modified":"2025-07-02T12:01:44","modified_gmt":"2025-07-02T04:01:44","slug":"%e9%aa%a8%e9%ab%93%e5%a2%9e%e7%94%9f%e7%95%b0%e5%b8%b8%e7%b6%9c%e5%90%88%e7%97%87-mds-%e7%99%8c%e7%97%87","status":"publish","type":"cancer_type","link":"https:\/\/allcancer.com\/hk\/%e7%99%8c%e7%97%87\/%e9%aa%a8%e9%ab%93%e5%a2%9e%e7%94%9f%e7%95%b0%e5%b8%b8%e7%b6%9c%e5%90%88%e7%97%87-mds-%e7%99%8c%e7%97%87\/","title":{"rendered":"\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)"},"content":{"rendered":"

\u4ec0\u9ebc\u662f\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)\uff1f<\/h2>\n

\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)<\/strong> \u4ee3\u8868\u4e00\u7cfb\u5217\u4ee5\u9aa8\u9ad3\u7d30\u80de\u7e41\u6b96\u7570\u5e38\u70ba\u7279\u5fb5\u7684\u7570\u8cea\u6027\u8840\u6db2\u75be\u75c5\u3002\u9019\u4e9b\u60c5\u6cc1\u6703\u7834\u58de\u6b63\u5e38\u7684\u9020\u8840\u529f\u80fd\uff0c\u5c0e\u81f4\u5404\u7a2e\u7d30\u80de\u6e1b\u5c11\u75c7\uff0c\u5c24\u5176\u662f\u8ca7\u8840\u3001\u767d\u8840\u7403\u6e1b\u5c11\u75c7\u548c\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\u3002<\/p>\n

\u77ad\u89e3\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u9996\u5148\u8981\u77ad\u89e3\u5176\u751f\u7269\u57fa\u790e\u3002MDS \u6d89\u53ca\u9020\u8840\u5e79\u7d30\u80de\u4e0d\u53d7\u63a7\u5236\u7684\u589e\u6b96\u3001\u5206\u5316\u969c\u7919\u53ca\u51cb\u4ea1\u589e\u52a0\u3002\u5065\u5eb7\u7684\u9020\u8840\u904e\u7a0b\u4e2d\uff0c\u8840\u7d30\u80de\u6703\u6b63\u5e38\u6210\u719f\uff0c\u4f46\u53d7 MDS \u5f71\u97ff\u7684\u7d30\u80de\u537b\u7121\u6cd5\u6b63\u5e38\u6210\u719f\uff0c\u5f80\u5f80\u505c\u7559\u5728\u672a\u6210\u719f\u968e\u6bb5\uff0c\u4e26\u55aa\u5931\u5176\u529f\u80fd\u3002\u56e0\u6b64\uff0c\u60a3\u8005\u901a\u5e38\u6703\u7d93\u6b77\u6162\u6027\u8ca7\u8840\uff0c\u4e26\u4e14\u66f4\u5bb9\u6613\u53d7\u5230\u611f\u67d3\u548c\u51fa\u8840\u767c\u4f5c\u3002<\/p>\n

\u5728\u65b0\u9673\u4ee3\u8b1d\u7684\u5c64\u9762\u4e0a\uff0cMDS \u767c\u73fe\u7684\u764c\u7d30\u80de\u5c55\u73fe\u51fa\u7368\u7279\u7684\u5f31\u9ede\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u9019\u4e9b\u60e1\u6027\u7d30\u80de\u5c55\u73fe\u4e86\u6c83\u4f2f\u683c\u6548\u61c9 (Warburg effect)\uff1a\u5c0d\u7cd6\u9175\u89e3\u7684\u4f9d\u8cf4\u589e\u52a0\uff0c\u5373\u4f7f\u5728\u6c27\u6c23\u5145\u8db3\u7684\u60c5\u6cc1\u4e0b\u4e5f\u662f\u5982\u6b64\u3002\u9019\u7a2e\u4e0d\u898f\u5247\u7684\u65b0\u9673\u4ee3\u8b1d\u4f7f\u764c\u7d30\u80de\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u5065\u5eb7\u7d30\u80de\u5feb\u7d04 200 \u500d\uff0c\u56e0\u6b64\u81e8\u5e8a\u91ab\u5e2b\u53ef\u4ee5\u900f\u904e\u5275\u65b0\u7684\u65b0\u9673\u4ee3\u8b1d\u7642\u6cd5\u5229\u7528\u9019\u7a2e\u7279\u6027\u3002<\/p>\n

\u64da\u4f30\u8a08\uff0c\u5168\u7403\u6bcf\u5e74\u65b0\u8a3a\u65b7\u51fa\u8fd1 100,000 \u500b\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u75c5\u4f8b (World Health Organization, 2024)\u3002\u96d6\u7136\u6b64\u75c5\u76f8\u5c0d\u7f55\u898b\uff0c\u4f46\u5176\u767c\u75c5\u7387\u96a8\u8457\u5e74\u9f61\u589e\u9577\u800c\u986f\u8457\u589e\u52a0\uff0c\u5c24\u5176\u662f\u5728 60 \u6b72\u4e4b\u5f8c\u3002\u7279\u5225\u662f\u5728\u9999\u6e2f\uff0c\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3 (2025) \u7684\u8cc7\u6599\u986f\u793a\uff0c\u6bcf\u5e74\u7d04\u6709 400 \u500b\u65b0\u7684\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u75c5\u4f8b\uff0c\u4e3b\u8981\u767c\u751f\u5728 65 \u6b72\u4ee5\u4e0a\u7684\u4eba\u58eb\u8eab\u4e0a\u3002<\/p>\n

\u4e9e\u6d32\u53d7\u5f71\u97ff\u4eba\u53e3\u53ca\u6d41\u884c\u75c5\u5b78<\/h3>\n

\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u4e3b\u8981\u5f71\u97ff\u8001\u5e74\u4eba\u7fa4\uff0c\u60a3\u8005\u78ba\u8a3a\u6642\u7684\u4e2d\u4f4d\u5e74\u9f61\u63a5\u8fd1 70 \u6b72\u3002\u5c31\u6027\u5225\u800c\u8a00\uff0c\u7537\u6027\u7684\u767c\u75c5\u7387\u8f03\u9ad8\uff0c\u6bcf 1.5 \u540d\u5973\u6027\u60a3\u8005\u7d04\u6709 1.5 \u540d\u7537\u6027\u60a3\u8005\u3002\u907a\u50b3\u548c\u74b0\u5883\u56e0\u7d20\u5c0d\u4e9e\u6d32\u4eba\u53e3\u7684\u5730\u57df\u5dee\u7570\u6709\u986f\u8457\u7684\u5f71\u97ff\uff0c\u6d41\u884c\u75c5\u5b78\u7814\u7a76\u7a81\u986f\u4e86\u4e9e\u6d32\u5730\u5340\u767c\u75c5\u7387\u548c\u4e9e\u578b\u6bd4\u4f8b\u7684\u5dee\u7570\u3002<\/p>\n

\u5728\u4e9e\u6d32\u4eba\u53e3\u4e2d\uff0c\u5148\u524d\u7684\u5316\u5b78\u6cbb\u7642\u6216\u653e\u5c04\u6cbb\u7642\u3001\u74b0\u5883\u6bd2\u7d20\u63a5\u89f8\u4ee5\u53ca\u67d0\u4e9b\u907a\u50b3\u50be\u5411\u7b49\u56e0\u7d20\uff0c\u90fd\u662f\u5c0e\u81f4 MDS \u98a8\u96aa\u7684\u91cd\u8981\u56e0\u7d20\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u9999\u6e2f\u548c\u5176\u4ed6\u4e9e\u6d32\u767c\u9054\u5730\u5340\u7684\u767c\u75c5\u7387\u76f8\u5c0d\u8f03\u9ad8\uff0c\u90e8\u5206\u539f\u56e0\u8207\u58fd\u547d\u589e\u9577\u3001\u74b0\u5883\u58d3\u529b\u3001\u90fd\u5e02\u5de5\u696d\u5316\u548c\u4eba\u53e3\u8001\u5316\u6709\u95dc\u3002<\/p>\n

\u5c0d\u75c5\u60a3\u7684\u60c5\u7dd2\u548c\u8eab\u9ad4\u5f71\u97ff<\/h3>\n

\u9762\u81e8\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u8a3a\u65b7\u7684\u60a3\u8005\u901a\u5e38\u6703\u7d93\u6b77\u5de8\u5927\u7684\u60c5\u7dd2\u58d3\u529b\u548c\u8eab\u9ad4\u9650\u5236\u3002\u5e38\u898b\u7684\u75c7\u72c0\u5305\u62ec\u56b4\u91cd\u75b2\u52de\u3001\u53cd\u8986\u611f\u67d3\u3001\u5bb9\u6613\u7600\u50b7\u3001\u547c\u5438\u56f0\u96e3\u4ee5\u53ca\u983b\u7e41\u51fa\u8840\u7b49\uff0c\u9019\u4e9b\u75c7\u72c0\u6703\u56b4\u91cd\u5f71\u97ff\u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u3002\u5fc3\u7406\u5065\u5eb7\u65b9\u9762\u7684\u554f\u984c\uff0c\u5c24\u5176\u662f\u7126\u616e\u548c\u6182\u9b31\uff0c\u5e38\u4f34\u96a8\u8eab\u9ad4\u4e0a\u7684\u8868\u73fe\uff0c\u7a81\u986f\u51fa\u5c0d\u75c5\u60a3\u63d0\u4f9b\u9ad4\u6064\u7684\u8de8\u9818\u57df\u7167\u8b77\u7684\u5fc5\u8981\u6027\u3002<\/p>\n

    \n
  • \u8ca7\u8840\u5f15\u8d77\u7684\u75b2\u52de\u6703\u56b4\u91cd\u59a8\u7919\u65e5\u5e38\u6d3b\u52d5\u3002<\/li>\n
  • \u51fa\u8840\u554f\u984c\uff0c\u5f9e\u8f15\u5fae\u7684\u7600\u9752\u5230\u56b4\u91cd\u7684\u51fa\u8840\uff0c\u90fd\u6703\u9020\u6210\u65e5\u5e38\u751f\u6d3b\u4e0a\u7684\u7126\u616e\u3002<\/li>\n
  • \u7531\u65bc\u767d\u8840\u7403\u6578\u91cf\u964d\u4f4e\uff0c\u56e0\u6b64\u7d93\u5e38\u767c\u751f\u611f\u67d3\uff0c\u9032\u4e00\u6b65\u9650\u5236\u4e86\u75c5\u60a3\u7684\u884c\u52d5\u80fd\u529b\uff0c\u4e26\u6e1b\u5c11\u4e86\u793e\u5340\u548c\u793e\u6703\u53c3\u8207\u3002<\/li>\n<\/ul>\n

    \u91dd\u5c0d\u9019\u4e9b\u6311\u6230\uff0cAllCancer \u7684\u9999\u6e2f\u4ee3\u8b1d\u7642\u6cd5\u5f15\u5165\u4e86\u91dd\u5c0d\u764c\u7d30\u80de\u4ee3\u8b1d\u6f0f\u6d1e\u7684\u9769\u547d\u6027\u65b9\u6cd5\u3002\u6709\u95dc\u8a73\u7d30\u7684\u6cbb\u7642\u65b9\u6cd5\uff0c\u8acb\u700f\u89bd\u6211\u5011\u5c08\u9580\u7684\u764c\u75c7\u751f\u7269\u5b78\u6559\u80b2\u7db2\u9801\u548c\u4ee3\u8b1d\u816b\u7624\u5b78\u5275\u65b0\u3002<\/p>\n

    \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u7684\u6210\u56e0\u8207\u98a8\u96aa\u56e0\u7d20<\/h2>\n

    \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u7684\u78ba\u5207\u81f4\u75c5\u56e0\u7d20\u4ecd\u7136\u662f\u591a\u65b9\u9762\u7684\uff0c\u5305\u62ec\u907a\u50b3\u3001\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u7684\u5f71\u97ff\u3002\u8b58\u5225\u9019\u4e9b\u56e0\u7d20\u6709\u52a9\u65bc\u6709\u6548\u9810\u9632\u548c\u65e9\u671f\u5e72\u9810\uff0c\u5c0d\u60a3\u8005\u7684\u7642\u6548\u4e0d\u53ef\u6216\u7f3a\u3002<\/p>\n

    \u907a\u50b3\u548c\u5206\u5b50\u56e0\u7d20<\/h3>\n

    \u907a\u50b3\u7570\u5e38\u662f\u767c\u751f MDS \u7684\u6838\u5fc3\u539f\u56e0\u3002\u5178\u578b\u7684\u5206\u5b50\u7578\u8b8a\u5305\u62ec\u67d3\u8272\u9ad4\u7f3a\u5931\u3001\u91cd\u8907\u6216\u6613\u4f4d\u3002\u6700\u91cd\u8981\u7684\u662f\uff0c\u6d89\u53ca TET2\u3001SF3B1\u3001ASXL1\u3001TP53 \u548c RUNX1 \u7b49\u57fa\u56e0\u7684\u7a81\u8b8a\u7d93\u5e38\u51fa\u73fe\u5728\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\u60a3\u8005\u8eab\u4e0a\u3002\u9019\u4e9b\u7a81\u8b8a\u5c0d\u7d30\u80de\u5206\u5316\u53d7\u640d\u548c\u7d30\u80de\u51cb\u4ea1\u589e\u5f37\u6709\u91cd\u5927\u5f71\u97ff\u3002<\/p>\n

      \n
    • SF3B1 \u7a81\u53d8\u662f\u73af\u72b6\u5de9\u819c\u6bcd\u7ec6\u80de\u4e9a\u578b\u60a3\u8005\u7684\u7279\u5f81\u3002<\/li>\n
    • TP53 \u57fa\u56e0\u7a81\u8b8a\u8207\u56b4\u91cd\u7684\u8010\u85e5\u6027\u75be\u75c5\u8868\u578b\u76f8\u95dc\u3002<\/li>\n
    • ASXL1 \u57fa\u56e0\u7a81\u8b8a\u5177\u6709\u4e0d\u826f\u7684\u9810\u5f8c\u610f\u7fa9\u3002<\/li>\n<\/ul>\n

      \u74b0\u5883\u56e0\u7d20<\/h3>\n

      \u66b4\u9732\u65bc\u6bd2\u6027\u5291\u6703\u986f\u8457\u589e\u52a0 MDS \u98a8\u96aa\u3002\u5148\u524d\u7684\u5316\u7642\u6216\u653e\u5c04\u6cbb\u7642\u6703\u9020\u6210\u5f88\u5927\u7684\u98a8\u96aa\uff0c\u53cd\u6620\u51fa\u7e7c\u767c\u6027 MDS \u7684\u589e\u52a0\u3002\u6b64\u5916\uff0c\u9577\u671f\u66b4\u9732\u65bc\u74b0\u5883\u81f4\u764c\u7269\uff08\u5305\u62ec\u82ef\u548c\u91cd\u91d1\u5c6c\uff09\u4e5f\u662f MDS \u7b49\u8840\u6db2\u60e1\u6027\u816b\u7624\u7684\u4e00\u5927\u98a8\u96aa\u56e0\u7d20\u3002<\/p>\n

      \u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20\u8207\u9810\u9632<\/h3>\n

      \u5118\u7ba1\u8207\u907a\u50b3\u6216\u74b0\u5883\u5f71\u97ff\u76f8\u6bd4\uff0c\u98f2\u98df\u548c\u98f2\u9152\u7b49\u751f\u6d3b\u65b9\u5f0f\u7684\u5f71\u97ff\u8f03\u4e0d\u986f\u8457\uff0c\u4f46\u7dad\u6301\u5065\u5eb7\u7684\u751f\u6d3b\u65b9\u5f0f\u53ef\u5927\u5e45\u964d\u4f4e\u6574\u9ad4\u7f79\u60a3\u764c\u75c7\u548c\u8840\u6db2\u7cfb\u7d71\u75be\u75c5\u7684\u98a8\u96aa\u3002\u6700\u8fd1\uff0c\u79d1\u5b78\u7814\u7a76\u63a2\u7d22\u4e86\u764c\u7d30\u80de\u7368\u7279\u7684\u65b0\u9673\u4ee3\u8b1d\u8106\u5f31\u6027\uff0c\u5305\u62ec\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u4f9d\u8cf4\u6027\uff0c\u70ba\u65b0\u578b\u9810\u9632\u7b56\u7565\u548c\u91dd\u5c0d\u6027\u6cbb\u7642\u92ea\u8def\u3002<\/p>\n

        \n
      • \u512a\u5316\u71df\u990a\u548c\u5b9a\u671f\u5f9e\u4e8b\u9ad4\u529b\u6d3b\u52d5\u53ef\u5c07\u6c27\u5316\u58d3\u529b\u548c\u767c\u708e\u6e1b\u81f3\u6700\u4f4e\u3002<\/li>\n
      • \u907f\u514d\u7159\u8349\u548c\u904e\u91cf\u9152\u7cbe\u53ef\u5927\u5e45\u964d\u4f4e\u7f79\u764c\u98a8\u96aa\u3002<\/li>\n
      • \u4ee5\u6c83\u4f2f\u683c\u6548\u61c9\u548c\u8c37\u6c28\u9170\u80fa\u4e0a\u766e\u70ba\u76ee\u6a19\u7684\u4ee3\u8b1d\u7642\u6cd5\u986f\u793a\u51fa\u4e86\u826f\u597d\u7684\u9810\u9632\u548c\u6cbb\u7642\u6f5b\u529b\uff0c\u5c24\u5176\u8207\u9999\u6e2f\u5168\u79d1\u764c\u75c7\u4e2d\u5fc3\u6240\u63a1\u7528\u7684\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\u5275\u65b0\u65b9\u6cd5\u6709\u95dc\u3002<\/li>\n<\/ul>\n

        \u4e9e\u6d32\u7279\u6709\u98a8\u96aa\u56e0\u7d20\u8207\u9999\u6e2f\u8da8\u52e2<\/h3>\n

        \u5340\u57df\u5206\u6790\u986f\u793a\u4e9e\u6d32\u4eba\u53e3\u7684\u7279\u5b9a\u98a8\u96aa\u56e0\u7d20\u8f03\u70ba\u7a81\u51fa\u3002\u9999\u6e2f\u4eba\u53e3\u8001\u5316\u3001\u5de5\u696d\u767c\u5c55\u5c0e\u81f4\u82ef\u66b4\u9732\u7684\u666e\u904d\u6027\uff0c\u4ee5\u53ca\u5316\u7642\u8a98\u767c\u7684\u7e7c\u767c\u6027 MDS \u75c5\u4f8b\u8f03\u9ad8\u7684\u767c\u75c5\u7387\uff0c\u5c0d\u5340\u57df\u6d41\u884c\u75c5\u5b78\u6709\u986f\u8457\u7684\u5f71\u97ff\u3002<\/p>\n

        \u5728\u4e9e\u6d32\uff0c\u53ca\u6642\u7be9\u6aa2\u548c\u65e9\u671f\u767c\u73fe\u5c0d\u65bc\u60a3\u8005\u7684\u826f\u597d\u6cbb\u7642\u7d50\u679c\u4ecd\u7136\u975e\u5e38\u91cd\u8981\uff0c\u53ef\u660e\u986f\u63d0\u9ad8\u5b58\u6d3b\u7387\u4e26\u6e1b\u5c11\u8907\u96dc\u7684\u75c5\u60c5\u9032\u5c55\u3002AllCancer \u63d0\u4f9b\u5168\u9762\u7684\u7be9\u6aa2\u53ca\u8a3a\u65b7\u670d\u52d9\uff0c\u53ef\u4e3b\u52d5\u63d0\u4f9b\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u5065\u5eb7\u7ba1\u7406\u3002<\/p>\n

        \u82e5\u8981\u9032\u4e00\u6b65\u77ad\u89e3 MDS \u7684\u98a8\u96aa\uff0c\u8acb\u53c3\u8003\u503c\u5f97\u4fe1\u8cf4\u7684\u5916\u90e8\u91ab\u7642\u8cc7\u6e90\uff0c\u4f8b\u5982\u4e16\u754c\u885b\u751f\u7d44\u7e54\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u3001\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3\u548c\u7f8e\u570b\u570b\u5bb6\u764c\u75c7\u7814\u7a76\u6240\uff0c\u6216\u806f\u7d61\u6211\u5011\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u5c08\u5bb6\uff0c\u4ee5\u7372\u5f97\u8a73\u7d30\u7684\u8aee\u8a62\u548c\u65e9\u671f\u7be9\u6aa2\u5efa\u8b70\u3002<\/p>\n

        \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u75c7\u72c0<\/h2>\n

        \u53ca\u65e9\u767c\u73fe\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u75c7\u72c0\u53ef\u986f\u8457\u6539\u5584\u6cbb\u7642\u6548\u679c\u548c\u6574\u9ad4\u9810\u5f8c\u3002\u75c7\u72c0\u6703\u56e0\u75be\u75c5\u968e\u6bb5\u53ca\u500b\u5225\u75c5\u60a3\u7684\u7279\u5fb5\u800c\u6709\u6240\u4e0d\u540c\u3002\u5982\u679c\u60a8\u767c\u73fe\u4ee5\u4e0b\u4efb\u4f55\u75c7\u72c0\uff0c\u52d9\u5fc5\u53ca\u6642\u5c31\u91ab\u3002<\/p>\n

          \n
        • \u75b2\u52de\u548c\u865b\u5f31\uff1a<\/strong> \u6301\u7e8c\u75b2\u52de\u662f\u6700\u65e9\u7684\u6307\u6a19\u4e4b\u4e00\uff0c\u9019\u662f\u7531\u65bc\u8ca7\u8840\u76f8\u95dc\u7684\u6c27\u6c23\u50b3\u8f38\u80fd\u529b\u964d\u4f4e\u6240\u81f4\u3002<\/li>\n
        • \u547c\u5438\u6025\u4fc3\uff1a<\/strong> \u56e0\u8840\u7403\u88fd\u9020\u6548\u7387\u4f4e\u800c\u9020\u6210\u7684\u8840\u7d05\u7d20\u6fc3\u5ea6\u964d\u4f4e\u6703\u5c0e\u81f4\u547c\u5438\u56f0\u96e3\uff0c\u5c24\u5176\u662f\u5728\u9ad4\u529b\u6d88\u8017\u6642\u3002<\/li>\n
        • \u819a\u8272\u84bc\u767d\u6216\u7570\u5e38\uff1a<\/strong> \u7d05\u8840\u7403\u6578\u91cf\u6e1b\u5c11\u6703\u5c0e\u81f4\u76ae\u819a\u84bc\u767d\u6216\u6307\u7532\u5e8a\u6216\u9ecf\u819c\u51fa\u73fe\u7570\u5e38\u892a\u8272\u3002<\/li>\n
        • \u7d93\u5e38\u611f\u67d3\uff1a<\/strong> \u7531\u65bc\u8840\u6db2\u5faa\u74b0\u4e2d\u7684\u4e2d\u6027\u7c92\u7d30\u80de\u6e1b\u5c11\uff0c\u60a3\u8005\u6703\u66f4\u5bb9\u6613\u547c\u5438\u9053\u611f\u67d3\u3001\u5c3f\u9053\u611f\u67d3\u6216\u76ae\u819a\u611f\u67d3\u3002<\/li>\n
        • \u5bb9\u6613\u7600\u50b7\u6216\u51fa\u8840\uff1a<\/strong> \u8840\u5c0f\u677f\u8a08\u6578\u904e\u4f4e\uff08\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff09\u6703\u9020\u6210\u7600\u50b7\u6216\u7600\u6591\u81ea\u52d5\u51fa\u73fe\uff0c\u6216\u5728\u8f15\u5fae\u53d7\u50b7\u5f8c\u51fa\u73fe\u3002<\/li>\n
        • \u767c\u71d2<\/strong> \u53cd\u8986\u767c\u71d2\u6216\u539f\u56e0\u4e0d\u660e\u7684\u767c\u71d2\u53ef\u80fd\u8868\u793a\u6f5b\u5728\u611f\u67d3\u6216\u767c\u708e\uff0c\u7e7c\u767c\u65bc\u767d\u8840\u7403\u529f\u80fd\u7570\u5e38\u3002<\/li>\n
        • \u6e1b\u80a5\uff1a<\/strong> \u4e0d\u660e\u539f\u56e0\u6216\u975e\u6545\u610f\u7684\u9ad4\u91cd\u4e0b\u964d\u53ef\u80fd\u662f\u7531\u65bc\u7d30\u80de\u4ee3\u8b1d\u589e\u52a0\u3001\u98df\u617e\u4e0d\u632f\u6216\u5168\u8eab\u6027\u767c\u708e\u6240\u9020\u6210\u3002<\/li>\n
        • \u9aa8\u9abc\u75bc\u75db\u6216\u4e0d\u9069\uff1a<\/strong> \u96d6\u7136\u6bd4\u8d77\u5176\u4ed6\u60e1\u6027\u816b\u7624\u8f03\u4e0d\u5e38\u898b\uff0c\u4f46\u5076\u723e\u4e5f\u6703\u56e0\u70ba\u9aa8\u9ad3\u8154\u64f4\u5927\u6216\u7570\u5e38\u7d30\u80de\u6d78\u6f64\u800c\u51fa\u73fe\u6df1\u5c64\u9aa8\u75db\u3002<\/li>\n
        • \u591c\u9593\u51fa\u6c57\uff1a<\/strong> \u665a\u4e0a\u51fa\u6c57\u904e\u591a\uff0c\u53cd\u6620\u51fa\u8207\u75be\u75c5\u9032\u7a0b\u76f8\u95dc\u7684\u6f5b\u5728\u9ad8\u4ee3\u8b1d\u72c0\u614b\u3002<\/li>\n<\/ul>\n

          \u7576\u75be\u75c5\u9032\u5c55\u5230\u66f4\u5177\u4fb5\u8972\u6027\u7684\u968e\u6bb5\u6216\u8f49\u8b8a\u70ba\u6025\u6027\u9ad3\u7d30\u80de\u767d\u8840\u75c5 (AML)\uff0c\u75c7\u72c0\u5c31\u6703\u52a0\u5287\u4e14\u8d8a\u4f86\u8d8a\u56b4\u91cd\uff0c\u7a81\u986f\u51fa\u65e9\u671f\u767c\u73fe\u548c\u4ecb\u5165\u7684\u8feb\u5207\u6027\u3002<\/p>\n

          \u65e9\u671f\u75c7\u72c0\uff1a<\/h3>\n

          \u901a\u5e38\uff0c\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u6703\u51fa\u73fe\u5fae\u5999\u7684\u65e9\u671f\u8b66\u793a\u75c7\u72c0\uff1a<\/p>\n

            \n
          • \u6301\u7e8c\u6027\u8f15\u5ea6\u8ca7\u8840<\/li>\n
          • \u8f15\u5ea6\u75b2\u52de\u548c\u55dc\u7761<\/li>\n
          • \u5c11\u91cf\u6216\u5076\u723e\u51fa\u8840<\/li>\n
          • \u5076\u767c\u6027\u8f15\u5fae\u611f\u67d3<\/li>\n<\/ul>\n

            \u665a\u671f\u75c7\u72c0\uff1a<\/h3>\n

            \u96a8\u8457\u7d9c\u5408\u75c7\u7684\u9032\u5c55\uff0c\u60a3\u8005\u7684\u75c7\u72c0\u6703\u8b8a\u5f97\u66f4\u660e\u986f\uff1a<\/p>\n

              \n
            • \u56b4\u91cd\u8ca7\u8840\uff0c\u4f34\u6709\u660e\u986f\u7684\u547c\u5438\u56f0\u96e3\u548c\u75b2\u618a\u75c7\u72c0<\/li>\n
            • \u53cd\u8986\u56b4\u91cd\u611f\u67d3\uff0c\u901a\u5e38\u9700\u8981\u4f4f\u9662\u6cbb\u7642<\/li>\n
            • \u56e0\u8840\u5c0f\u677f\u56b4\u91cd\u6e1b\u5c11\u800c\u5f15\u767c\u7684\u56b4\u91cd\u51fa\u8840\u767c\u4f5c<\/li>\n
            • \u6975\u5ea6\u6d88\u7626\u548c\u60e1\u75c5\u8cea<\/li>\n
            • \u7531\u65bc\u80da\u6ce1\uff08\u672a\u6210\u719f\u7d30\u80de\uff09\u589e\u52a0\u800c\u51fa\u73fe\u985e\u4f3c\u767d\u8840\u75c5\u7684\u75c7\u72c0<\/li>\n<\/ul>\n

              \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u5206\u671f\u8207\u5b58\u6d3b\u7387<\/h2>\n

              \u77ad\u89e3\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u5206\u671f\u6709\u52a9\u65bc\u60a3\u8005\u548c\u5bb6\u5c6c\u66f4\u597d\u5730\u70ba\u500b\u4eba\u5316\u6cbb\u7642\u8a08\u5283\u548c\u6f5b\u5728\u7d50\u679c\u505a\u597d\u6e96\u5099\u3002\u7279\u5225\u662f\u5728\u4e9e\u6d32\u548c\u9999\u6e2f\uff0c\u91ab\u7642\u4fdd\u5065\u5be6\u52d9\u8457\u91cd\u900f\u904e\u5168\u9762\u7684\u793e\u5340\u5916\u5c55\u3001\u7be9\u6aa2\u548c\u75c5\u60a3\u6559\u80b2\u6d3b\u52d5\u9032\u884c\u65e9\u671f\u6aa2\u6e2c\u3002<\/p>\n

              \u7b2c 1 \u968e\u6bb5 - \u65e9\u671f\u53ca\u4f4e\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)<\/h3>\n

              \u4e3b\u8981\u7279\u5fb5\u70ba\u8f15\u5ea6\u5168\u8840\u7ec6\u80de\u6e1b\u5c11\u3001\u53ef\u63a7\u5236\u7684\u8ca7\u8840\uff0c\u4ee5\u53ca\u9aa8\u9ad3\u4e2d\u8840\u5c0f\u677f\u6e1b\u5c11 (\u4f4e\u65bc 5%)\u3002\u60a3\u8005\u7684\u751f\u6d3b\u54c1\u8cea\u5927\u81f4\u4e0d\u53d7\u5f71\u97ff\uff0c\u6cbb\u7642\u65b9\u6848\u4ee5\u63a7\u5236\u75c7\u72c0\u548c\u6e1b\u5c11\u4f75\u767c\u75c7\u70ba\u76ee\u6a19\u3002<\/p>\n

                \n
              • \u6cbb\u7642\u65b9\u6848\u5305\u62ec\u4fc3\u7d05\u8840\u7403\u751f\u6210\u5291 (ESAs)\u3001\u8f38\u8840\u3001\u4f7f\u7528\u751f\u9577\u56e0\u5b50\u7684\u652f\u6301\u6027\u7167\u8b77\uff0c\u4ee5\u53ca\u9810\u9632\u9435\u8ca0\u8377\u904e\u91cd\u7684\u9435\u87af\u5408\u7642\u6cd5\u3002<\/li>\n
              • \u5b58\u6d3b\u7387\uff1a\u6839\u64da\u9999\u6e2f\u91ab\u7642\u6a5f\u69cb\u6700\u8fd1\u7684\u7814\u7a76\u5831\u544a\uff0c\u5728\u9069\u7576\u7684\u652f\u63f4\u548c\u9810\u9632\u6027\u7167\u8b77\u7b56\u7565\u4e0b\uff0c5 \u5e74\u5b58\u6d3b\u7387\u9ad8\u9054 80-90%\u3002<\/li>\n<\/ul>\n

                \u7b2c 2 \u968e\u6bb5 - \u4e2d\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)<\/h3>\n

                \u8868\u73fe\u70ba\u9aa8\u9ad3\u7d30\u80de\u5c11\u91cf\u589e\u52a0 (5-10%)\u3001\u986f\u8457\u7684\u5168\u8840\u7d30\u80de\u6e1b\u5c11\u3001\u7d93\u5e38\u611f\u67d3\uff0c\u4ee5\u53ca\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u7684\u6301\u7e8c\u75b2\u52de\u3002<\/p>\n

                  \n
                • \u6cbb\u7642\u9078\u64c7\uff1a\u7d50\u5408\u9776\u5411\u7642\u6cd5\u3001\u4f4e\u7532\u57fa\u5316\u5291 (5-azacitidine, Decitabine) \u8207\u652f\u6301\u6027\u7167\u8b77\u63aa\u65bd\u3002<\/li>\n
                • \u5b58\u6d3b\u7387\uff1a\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 60-75%\uff0c\u53cd\u6620\u8f03\u9ad8\u98a8\u96aa\u4ee5\u53ca\u76ee\u524d\u53ef\u900f\u904e\u8207\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u548c MD Anderson \u7b49\u5408\u4f5c\u7684\u5148\u9032\u9999\u6e2f\u816b\u7624\u4e2d\u5fc3\u63d0\u4f9b\u7684\u4e2d\u7b49\u7642\u6548\u7642\u6cd5\u3002<\/li>\n<\/ul>\n

                  \u7b2c 3 \u671f - \u9ad8\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)<\/h3>\n

                  \u9020\u8840\u80fd\u529b\u8f03\u5dee\u3001\u9aa8\u9ad3\u7206\u88c2\u7a0b\u5ea6\u8f03\u9ad8\uff0810-20%\uff09\u3001\u6301\u7e8c\u611f\u67d3\u98a8\u96aa\u3001\u51fa\u8840\u4f75\u767c\u75c7\u589e\u52a0\u3001\u75c7\u72c0\u5feb\u901f\u60e1\u5316\u3002<\/p>\n

                    \n
                  • \u6cbb\u7642\u9078\u64c7\uff1a\u4f7f\u7528\u7532\u57fa\u5316\u6291\u5236\u5291 (Hypomethylating agents) \u9032\u884c\u7a4d\u6975\u6cbb\u7642\u3001\u9069\u5408\u7684\u5019\u9078\u4eba\u53ef\u8003\u616e\u7570\u57fa\u56e0\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d (HSCT)\uff0c\u4ee5\u53ca\u5148\u9032\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u65b9\u6cd5\u3002<\/li>\n
                  • \u5b58\u6d3b\u7387\uff1a\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 35-50%\uff0c\u53d6\u6c7a\u65bc\u60a3\u8005\u7684\u5065\u5eb7\u72c0\u6cc1\uff0c\u4ee5\u53ca\u9999\u6e2f\u548c\u4e2d\u570b\u5927\u9678\u5148\u9032\u7684\u7814\u7a76\u652f\u6301\u91ab\u9662\u662f\u5426\u63d0\u4f9b\u5e79\u7d30\u80de\u79fb\u690d\u670d\u52d9\u3002<\/li>\n<\/ul>\n

                    \u7b2c 4 \u671f - \u6975\u9ad8\u98a8\u96aa\u8207\u767d\u8840\u75c5\u8f49\u578b\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS)<\/h3>\n

                    \u7279\u5fb5\u70ba\u5927\u91cf\u9aa8\u9ad3\u7206\u88c2\u7d30\u80de (>20%)\u3001\u986f\u8457\u7684\u61b2\u5236\u6027\u75c7\u72c0\u3001\u56b4\u91cd\u7684\u5168\u8840\u7ec6\u80de\u6e1b\u5c11\uff0c\u4ee5\u53ca\u8fc5\u901f\u60e1\u5316\u6210\u6025\u6027\u9ad3\u7d30\u80de\u767d\u8840\u75c5 (AML)\u3002<\/p>\n

                      \n
                    • \u6cbb\u7642\u9078\u64c7\uff1a\u5f37\u5316\u7684\u5316\u7642\u65b9\u6848\u3001AML \u985e\u7684\u8a98\u5c0e\u6cbb\u7642\u3001\u91dd\u5c0d\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u4f9d\u8cf4\u6027\u7684\u5148\u9032\u4ee3\u8b1d\u7b56\u7565\uff0c\u4ee5\u5229\u7528\u6c83\u4f2f\u683c\u6548\u61c9\uff0c\u4e26\u76e1\u53ef\u80fd\u7dca\u6025\u8003\u616e\u9020\u8840\u5e79\u7d30\u80de\u79fb\u690d\u3002<\/li>\n
                    • \u5b58\u6d3b\u7387\uff1a\u9999\u6e2f\u9802\u5c16\u7684\u816b\u7624\u79d1\u91ab\u9662\u63d0\u4f9b\u6700\u5148\u9032\u7684\u8a2d\u5099\uff0c\u5f37\u8abf\u6301\u7e8c\u7684\u91ab\u7642\u9032\u6b65\u548c\u9ad4\u6064\u7684\u751f\u547d\u672b\u671f\u7642\u8b77\u65b9\u6cd5\uff0c\u7a4d\u6975\u7ba1\u7406\u75c5\u4eba\uff0c\u901a\u5e38\u7d04\u6709 20-30% \u7684 3 \u5e74\u5b58\u6d3b\u7387\u3002<\/li>\n<\/ul>\n

                      \u900f\u904e\u9999\u6e2f\u5148\u9032\u7684\u6280\u8853\u548c\u9ad4\u8cbc\u7684\u91ab\u7642\u8b77\u7406\uff0c\u500b\u4eba\u5316\u7684\u6cbb\u7642\u8a08\u5283\u53ef\u63d0\u9ad8\u4e0d\u540c\u968e\u6bb5 MDS \u7684\u5b58\u6d3b\u7387\u548c\u751f\u6d3b\u8cea\u7d20\u3002\u6211\u5011\u9f13\u52f5\u60a3\u8005\u548c\u5bb6\u5c6c\u8207\u816b\u7624\u79d1\u5c08\u79d1\u91ab\u751f\u9032\u884c\u5168\u9762\u7684\u8a0e\u8ad6\uff0c\u4ee5\u5145\u5206\u638c\u63e1\u4ed6\u5011\u7684\u9078\u64c7\u3002<\/p>\n

                      \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u6cbb\u7642\u65b9\u6848<\/h2>\n

                      \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7531\u65bc\u75c7\u72c0\u591a\u6a23\u4e14\u8907\u96dc\uff0c\u56e0\u6b64\u9700\u8981\u500b\u4eba\u5316\u7684\u6cbb\u7642\u65b9\u5f0f\u3002\u6cbb\u7642\u7b56\u7565\u901a\u5e38\u5305\u542b\u4e00\u7cfb\u5217\u7684\u5e72\u9810\u63aa\u65bd\uff0c\u5728\u7642\u6548\u8207\u751f\u6d3b\u54c1\u8cea\u4e4b\u9593\u53d6\u5f97\u5e73\u8861\uff0c\u4e26\u5bc6\u5207\u4f9d\u5faa\u75c5\u60a3\u7684\u7279\u5b9a\u56e0\u7d20\uff0c\u4f8b\u5982\u5e74\u9f61\u3001\u56b4\u91cd\u6027\u548c\u907a\u50b3\u7279\u5fb5\u3002<\/p>\n

                      \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u6a19\u6e96\u6cbb\u7642\u65b9\u6848<\/h3>\n

                      \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u7684\u5316\u5b78\u6cbb\u7642<\/h4>\n

                      \u5728\u9999\u6e2f\u53ca\u4e9e\u6d32\uff0c\u5316\u7642\uff0c\u7279\u5225\u662f\u4f4e\u7532\u57fa\u5316\u85e5\u7269\u5982\u963f\u624e\u80de\u82f7\u548c\u5730\u897f\u4ed6\u6ff1\uff0c\u65e9\u5df2\u88ab\u516c\u8a8d\u70ba\u6cbb\u7642\u9ad8\u98a8\u96aa\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7\uff08MDS\uff09\u7684\u57fa\u77f3\u3002\u9019\u4e9b\u85e5\u7269\u7684\u529f\u80fd\u662f\u4f7f DNA \u53bb\u7532\u57fa\u5316\u3001\u5f71\u97ff\u57fa\u56e0\u8868\u9054\u3001\u6e1b\u7de9\u7570\u5e38\u7d30\u80de\u5206\u88c2\uff0c\u6709\u52a9\u6539\u5584\u8840\u7d30\u80de\u8a08\u6578\u548c\u6e1b\u8f15\u75c7\u72c0\u3002<\/p>\n

                        \n
                      • \u963f\u624e\u80de\u82f7\uff1a\u5728\u98a8\u96aa\u8f03\u9ad8\u7684\u75c5\u60a3\u4e2d\uff0c\u986f\u793a\u6574\u9ad4\u53cd\u61c9\u7387 (ORR) \u7d04\u70ba 60%\u3002<\/li>\n
                      • Decitabine\uff1a\u8207\u963f\u624e\u80de\u82f7\u7684\u53cd\u61c9\u7387\u76f8\u4f3c\uff0c\u4f46\u6cbb\u7642\u6c7a\u5b9a\u4e3b\u8981\u53d6\u6c7a\u65bc\u81e8\u5e8a\u8868\u73fe\u3001\u6210\u672c\u4ee5\u53ca\u5728\u4e9e\u6d32\u7684\u53ef\u53ca\u6027\u3002<\/li>\n<\/ul>\n

                        \u5118\u7ba1\u6709\u5408\u7406\u7684\u7642\u6548\uff0c\u5316\u7642\u4ecd\u6709\u76f8\u7576\u5927\u7684\u98a8\u96aa\uff0c\u5c24\u5176\u662f\u8840\u6db2\u7cfb\u7d71\u6bd2\u6027\uff0c\u4f8b\u5982\u8ca7\u8840\u3001\u4e2d\u6027\u7c92\u8840\u7403\u6e1b\u5c11\u75c7\u548c\u8840\u5c0f\u677f\u6e1b\u5c11\u75c7\uff0c\u56e0\u6b64\u5fc5\u9808\u6301\u7e8c\u76e3\u6e2c\u3002<\/p>\n

                        \u652f\u63f4\u6027\u6cbb\u7642\u548c\u8f38\u8840<\/h4>\n

                        \u8a31\u591a\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u60a3\u8005\u6703\u7d93\u6b77\u6162\u6027\u8ca7\u8840\uff0c\u5fc5\u9808\u5b9a\u671f\u8f38\u8840\u624d\u80fd\u7dad\u6301\u8db3\u5920\u7684\u8840\u7d05\u7d20\u6c34\u5e73\u3002\u87af\u5408\u7642\u6cd5\u7d93\u5e38\u88ab\u7528\u4f86\u63a7\u5236\u9435\u8d85\u8ca0\u8377\uff0c\u9019\u662f\u6301\u7e8c\u8f38\u8840\u7684\u5e38\u898b\u526f\u4f5c\u7528\u3002<\/p>\n

                        \u751f\u9577\u56e0\u5b50\u6cbb\u7642<\/h4>\n

                        \u4f4e\u98a8\u96aa\u7684 MDS \u60a3\u8005\u901a\u5e38\u6703\u4f7f\u7528\u4fc3\u7d05\u8840\u7403\u751f\u6210\u7d20 (ESA) \u548c\u7c92\u7d30\u80de\u96c6\u843d\u523a\u6fc0\u56e0\u5b50 (G-CSF) \u7b49\u85e5\u7269\uff0c\u4ee5\u523a\u6fc0\u7d05\u8840\u7403\u548c\u767d\u8840\u7403\u7684\u5f62\u6210\uff0c\u9032\u800c\u63d0\u5347\u6574\u9ad4\u7684\u5065\u5eb7\u6210\u679c\u3002<\/p>\n

                        \u5e79\u7d30\u80de\u79fb\u690d<\/h4>\n

                        \u6cbb\u7642\u6f5b\u529b\u4e3b\u8981\u5728\u65bc\u7570\u9ad4\u5e79\u7d30\u80de\u79fb\u690d\uff0c\u4ee5\u5065\u5eb7\u7684\u6350\u8d08\u8005\u5e79\u7d30\u80de\u53d6\u4ee3\u8870\u7aed\u7684\u9aa8\u9ad3\u3002\u9019\u7a2e\u5bc6\u96c6\u7684\u7a0b\u5e8f\u53ea\u9069\u7528\u65bc\u5e74\u8f15\u3001\u9ad4\u683c\u5065\u5eb7\u3001\u6c92\u6709\u56b4\u91cd\u4f75\u767c\u75c7\u7684\u60a3\u8005\uff0c\u82e5\u8207\u5408\u9069\u7684\u6350\u8d08\u8005\u914d\u5c0d\uff0c\u5b58\u6d3b\u7387\u53ef\u905440-60%\u3002<\/p>\n

                        \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u65b0\u8208\u5275\u65b0\u7642\u6cd5<\/h3>\n

                        \u6700\u8fd1\u5c0d\u65bc\u764c\u7d30\u80de\u65b0\u9673\u4ee3\u8b1d\u7684\u6df1\u5165\u7814\u7a76\uff0c\u7279\u5225\u662f\u6c83\u4f2f\u683c\u6548\u61c9\u548c\u60e1\u6027\u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u7684\u4f9d\u8cf4\u6027\u589e\u52a0\uff0c\u70ba MDS \u63d0\u4f9b\u4e86\u6709\u6f5b\u529b\u7684\u6cbb\u7642\u76ee\u6a19\u3002<\/p>\n

                        \u91dd\u5c0d\u764c\u75c7\u80fd\u91cf\u7684\u4ee3\u8b1d\u7642\u6cd5<\/h4>\n

                        \u65b0\u578b\u4ee3\u8b1d\u816b\u7624\u5b78\u7b56\u7565\u65e8\u5728\u5229\u7528 MDS \u7d30\u80de\u7684\u7368\u7279\u5f31\u9ede\uff0c\u900f\u904e GLUT \u8f49\u904b\u9ad4 (GLUT1\/GLUT3) \u5e72\u64fe\u8461\u8404\u7cd6\u5438\u6536\u3002\u65b0\u9673\u4ee3\u8b1d\u816b\u7624\u5b78\u7b56\u7565\u7684\u76ee\u7684\u5728\u65bc\u5229\u7528 MDS \u7d30\u80de\u7368\u7279\u7684\u5f31\u9ede\uff0c\u900f\u904e GLUT \u8f49\u904b\u9ad4 (GLUT1\/GLUT3) \u64fe\u4e82\u8461\u8404\u7cd6\u7684\u651d\u53d6\u3002<\/p>\n

                        \u65b0\u8208\u8cc7\u6599\u986f\u793a\uff0c\u4ee3\u8b1d\u6291\u5236\u5291\u53ef\u88dc\u5145\u50b3\u7d71\u7642\u6cd5\u7684\u4e0d\u8db3\uff0c\u964d\u4f4e\u6bd2\u6027\uff0c\u4e26\u986f\u8457\u6539\u5584\u53cd\u61c9\u7387\u3002<\/p>\n

                        \u57fa\u65bc\u57fa\u56e0\u5206\u6790\u7684\u500b\u4eba\u5316\u6cbb\u7642<\/h4>\n

                        \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u816b\u7624\u7684\u6574\u5408\u57fa\u56e0\u6aa2\u6e2c\u548c\u6392\u5e8f\u70ba\u5305\u62ec\u9999\u6e2f\u5728\u5167\u7684\u8f03\u5c0f\u4e9e\u6d32\u4eba\u53e3\u63d0\u4f9b\u4e86\u7cbe\u7d30\u5316\u3001\u500b\u4eba\u5316\u7167\u8b77\u7684\u5bf6\u8cb4\u6a5f\u6703\u3002\u91dd\u5c0d\u7279\u5b9a\u7a81\u8b8a\uff08\u5982 TET2\u3001ASXL1 \u6216 SF3B1 \u7a81\u53d8\uff09\u7684\u6a19\u9776\u85e5\u7269\u6b63\u5728\u5168\u7403\u548c\u5730\u5340\u7684\u81e8\u5e8a\u8a66\u9a57\u4e2d\u7a4d\u6975\u9032\u884c\u8a55\u4f30\u3002<\/p>\n

                        \u9999\u6e2f\u548c\u4e9e\u6d32\u7684\u6cbb\u7642\u9650\u5236\u548c\u969c\u7919<\/h3>\n

                        \u53ef\u7528\u6027\u548c\u7121\u969c\u7919\u95dc\u6ce8<\/h4>\n

                        \u67d0\u4e9b\u4e9e\u6d32\u548c\u9999\u6e2f\u91ab\u9662\u7684\u6cbb\u7642\u9078\u64c7\u6709\u9650\uff0c\u9019\u9020\u6210\u4e86\u5f88\u5927\u7684\u56f0\u96e3\u3002\u7570\u9ad4\u5e79\u7d30\u80de\u79fb\u690d\u9700\u8981\u9ad8\u5ea6\u5c08\u696d\u5316\u7684\u91ab\u9662\u3001\u6350\u8d08\u8005\u548c\u57fa\u790e\u8a2d\u65bd\uff0c\u9019\u4e9b\u56e0\u7d20\u5728\u4e9e\u6d32\u5730\u5340\u4e26\u975e\u666e\u904d\u5b58\u5728\u3002<\/p>\n

                        \u7d93\u6fdf\u8207\u6587\u5316\u6311\u6230<\/h4>\n

                        \u6210\u672c\u9650\u5236\u3001\u91ab\u7642\u7167\u8b77\u7cfb\u7d71\u7684\u8ca0\u64d4\uff0c\u4ee5\u53ca\u5c0d\u5e79\u7d30\u80de\u79fb\u690d\u7b49\u5bc6\u96c6\u5f0f\u7642\u6cd5\u7684\u6587\u5316\u8003\u91cf\uff0c\u5f80\u5f80\u6c7a\u5b9a\u4e86\u8f03\u4e0d\u7a4d\u6975\u7684\u6cbb\u7642\u8def\u5f91\uff0c\u4f7f\u9810\u5f8c\u60c5\u6cc1\u548c\u75c5\u60a3\u5c0d\u65bc\u4ecb\u5165\u6cbb\u7642\u7684\u5c55\u671b\u66f4\u52a0\u8907\u96dc\u3002<\/p>\n

                        \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u75c7\u5019\u7fa4 (MDS) \u50b3\u7d71\u7642\u6cd5\u7684\u9650\u5236<\/h2>\n

                        \u5316\u7642\u7684\u7f3a\u9ede\u8207\u6bd2\u6027<\/h3>\n

                        \u5316\u5b78\u7642\u6cd5\u4e0d\u52a0\u9078\u64c7\u5730\u91dd\u5c0d\u5feb\u901f\u5206\u88c2\u7684\u7d30\u80de\uff0c\u5c0d\u5065\u5eb7\u7d44\u7e54\u548c\u8840\u7d30\u80de\u88fd\u9020\u6a5f\u5236\u9020\u6210\u91cd\u5927\u7684\u610f\u5916\u50b7\u5bb3\u3002\u986f\u8457\u7684\u526f\u4f5c\u7528\u5305\u62ec\u56b4\u91cd\u9aa8\u9ad3\u6291\u5236 (>78%)\u3001\u611f\u67d3\u98a8\u96aa\u589e\u52a0\u5c0e\u81f4\u4f4f\u9662\uff0c\u4ee5\u53ca\u5668\u5b98\u6bd2\u6027\uff0c\u5c24\u5176\u662f\u5fc3\u81df\u6bd2\u6027 (~23% \u767c\u751f\u7387)\u3002<\/p>\n

                          \n
                        • \u9aa8\u9ad3\u6291\u5236\u9020\u6210\u56b4\u91cd\u7d30\u80de\u6e1b\u5c11 - \u8ca7\u8840\u3001\u8840\u5c0f\u677f\u6e1b\u5c11\u3002<\/li>\n
                        • \u9ad8\u611f\u67d3\u98a8\u96aa\u5c0e\u81f4\u4f4f\u9662\u6642\u9593\u5ef6\u9577\u3002<\/li>\n
                        • \u5fc3\u808c\u6bd2\u6027\u5c0d\u751f\u6d3b\u54c1\u8cea\u548c\u5b58\u6d3b\u7387\u6709\u8ca0\u9762\u5f71\u97ff\u3002<\/li>\n<\/ul>\n

                          \u653e\u5c04\u6cbb\u7642\u7684\u526f\u4f5c\u7528<\/h3>\n

                          \u653e\u5c04\u6cbb\u7642\u96d6\u7136\u8f03\u5c11\u7528\u65bcMDS\uff0c\u5c24\u5176\u662f\u5728\u5e79\u7d30\u80de\u79fb\u690d\u6e96\u5099\u4e4b\u5916\uff0c\u4f46\u4e5f\u6709\u91cd\u5927\u98a8\u96aa\u3002\u6839\u64da\u300a\u7f8e\u570b\u816b\u7624\u5b78\u6703\u6703\u520a\u300b(JAMA Oncology)\uff0c2023\u5e74\uff0c\u5c0d\u5468\u570d\u5065\u5eb7\u7d44\u7e54\u7684\u640d\u5bb3\u7d93\u5e38\u5c0e\u81f4\u56b4\u91cd\u75b2\u52de\u3001\u76ae\u819a\u523a\u6fc0\u548c\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\uff0c\u8f3b\u5c04\u76f8\u95dc\u764c\u75c7\u7684\u98a8\u96aa\u589e\u52a0\u7d04300%\u3002<\/p>\n

                          \u5c0d\u665a\u671f\u75be\u75c5\u7684\u7642\u6548\u6709\u9650<\/h3>\n

                          \u5c0d\u65bc\u665a\u671f\u6216\u665a\u671f\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS)\uff0c\u5316\u7642\u548c\u652f\u6301\u7642\u6cd5\u7684\u7642\u6548\u4f4e\u5f97\u4ee4\u4eba\u5931\u671b\uff0c\u5ba2\u89c0\u53cd\u61c9\u7387\u4f4e\u65bc 21%\u3002\u6b64\u5916\uff0c\u5305\u62ec 400% \u589e\u5f37\u7684 DNA \u4fee\u5fa9\u9175\u7d20\u6d3b\u6027\u5728\u5167\u7684\u6f38\u9032\u5f0f\u5316\u7642\u6297\u85e5\u6a5f\u5236\uff0c\u6703\u963b\u7919\u6cbb\u7642\u6548\u679c\u4e26\u52a0\u5287\u75be\u75c5\u9032\u5c55\u3002<\/p>\n

                          \u624b\u8853\u98a8\u96aa\u8207\u4f75\u767c\u75c7<\/h3>\n

                          \u4ecb\u5165\u6027\u7a0b\u5e8f\uff08\u9aa8\u9ad3\u6d3b\u6aa2\u3001\u5e79\u7d30\u80de\u63a1\u96c6\uff09\u96d6\u7136\u5f88\u5c11\u7528\u65bc MDS \u7684\u50b3\u7d71\u6cbb\u7642\uff0c\u4f46\u4e5f\u6709\u5176\u56fa\u6709\u7684\u98a8\u96aa\uff0c\u5305\u62ec\u611f\u67d3\u3001\u7a0b\u5e8f\u4f75\u767c\u75c7\u3001\u51fa\u8840\uff0c\u4ee5\u53ca\u5728\u8a3a\u65b7\u548c\u6cbb\u7642\u7a0b\u5e8f\u4e2d\u8207\u93ae\u975c\u6216\u9ebb\u9189\u76f8\u95dc\u7684\u4e0d\u826f\u53cd\u61c9\u3002<\/p>\n

                          \u5c0d\u5065\u5eb7\u7684\u9577\u671f\u5f71\u97ff\u548c\u5c0d\u751f\u6d3b\u54c1\u8cea\u7684\u95dc\u6ce8<\/h3>\n

                          \u50b3\u7d71 MDS \u6cbb\u7642\u5e38\u898b\u7684\u9577\u671f\u5f8c\u679c\uff0c\u4f8b\u5982\u6162\u6027\u75b2\u52de\u3001\u6301\u7e8c\u611f\u67d3\u98a8\u96aa\u3001\u5fc3\u7406\u56f0\u64fe\uff0c\u4ee5\u53ca\u8ca7\u8840\u5f15\u8d77\u7684\u751f\u6d3b\u54c1\u8cea\u53d7\u640d\uff0c\u9032\u4e00\u6b65\u7a81\u986f\u51fa\u5c0d\u6709\u6548\u4e14\u6bd2\u6027\u5c0f\u7684\u66ff\u4ee3\u7642\u6cd5\u7684\u8feb\u5207\u9700\u8981\u3002<\/p>\n

                          \u7e3d\u7d50<\/h2>\n

                          \u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u60a3\u8005\u7684\u7167\u8b77\u5fc5\u9808\u4e0d\u65b7\u767c\u5c55\uff0c\u63a5\u53d7\u65b0\u79d1\u6280\u3001\u6839\u690d\u65bc\u907a\u50b3\u5b78\u7684\u500b\u4eba\u5316\u7642\u6cd5\uff0c\u4ee5\u53ca\u5275\u65b0\u7684\u4ee3\u8b1d\u7642\u6cd5\u3002\u512a\u5316\u9999\u6e2f\u53ca\u4e9e\u6d32\u7684\u91ab\u7642\u7167\u8b77\uff0c\u6709\u8cf4\u65bc\u900f\u904e\u53ef\u7372\u5f97\u7684\u5275\u65b0\u6cbb\u7642\u3001\u6539\u5584\u7684\u652f\u63f4\u670d\u52d9\u3001\u4ee5\u75c5\u60a3\u70ba\u4e2d\u5fc3\u7684\u6cbb\u7642\u7b56\u7565\uff0c\u4ee5\u53ca\u900f\u904e\u6301\u7e8c\u7684\u7814\u7a76\u548c\u53c3\u8207\u4f86\u71c3\u9ede\u5e0c\u671b\uff0c\u4ee5\u8d85\u8d8a\u76ee\u524d\u7684\u6cbb\u7642\u9650\u5236\u3002<\/p>","protected":false},"excerpt":{"rendered":"

                          \u5728 AllCancer \u63a2\u7d22\u9aa8\u9ad3\u589e\u751f\u7570\u5e38\u7d9c\u5408\u75c7 (MDS) \u7684\u75c7\u72c0\u3001\u5206\u671f\u548c\u9769\u547d\u6027\u7684 HK \u4ee3\u8b1d\u7642\u6cd5\u3002<\/p>","protected":false},"author":3,"featured_media":7384,"parent":0,"menu_order":0,"template":"","class_list":["post-7715","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type\/7715","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"author":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/users\/3"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media\/7384"}],"wp:attachment":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media?parent=7715"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}