{"id":7729,"date":"2025-07-01T20:55:10","date_gmt":"2025-07-01T12:55:10","guid":{"rendered":"https:\/\/allcancer.com\/cancer\/intraocular-melanoma-uveal-melanoma-2\/"},"modified":"2025-07-02T12:47:04","modified_gmt":"2025-07-02T04:47:04","slug":"%e7%9c%bc%e5%85%a7%e9%bb%91%e8%89%b2%e7%b4%a0%e7%98%a4-%e8%a6%96%e7%b6%b2%e8%86%9c%e9%bb%91%e8%89%b2%e7%b4%a0%e7%98%a4-%e7%99%8c%e7%97%87%e9%a1%9e%e5%9e%8b","status":"publish","type":"cancer_type","link":"https:\/\/allcancer.com\/hk\/%e7%99%8c%e7%97%87\/%e7%9c%bc%e5%85%a7%e9%bb%91%e8%89%b2%e7%b4%a0%e7%98%a4-%e8%a6%96%e7%b6%b2%e8%86%9c%e9%bb%91%e8%89%b2%e7%b4%a0%e7%98%a4-%e7%99%8c%e7%97%87%e9%a1%9e%e5%9e%8b\/","title":{"rendered":"\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09"},"content":{"rendered":"<h2 class=\"h2-cancertype\">\u4ec0\u9ebc\u662f <strong>\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/strong>?<\/h2>\n<p class=\"p-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624 (\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624) \u662f\u4e00\u7a2e\u7f55\u898b\u4f46\u56b4\u91cd\u7684\u764c\u75c7\uff0c\u7531\u9ed1\u8272\u7d20\u7d30\u80de (\u4f4d\u65bc\u773c\u7403\u8461\u8404\u819c\u7684\u8272\u7d20\u751f\u6210\u7d30\u80de) \u6240\u5f15\u8d77\u3002\u8981\u77ad\u89e3\u773c\u5167\u9ed1\u8272\u7d20\u7624 (\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624)\uff0c\u9996\u5148\u8981\u8a8d\u8b58\u5230\u9ed1\u8272\u7d20\u7d30\u80de\u901a\u5e38\u6703\u4fdd\u8b77\u773c\u775b\u514d\u53d7\u7d2b\u5916\u7dda\u7684\u50b7\u5bb3\uff0c\u4f46\u4e5f\u6703\u767c\u751f\u7570\u5e38\u8f49\u8b8a\uff0c\u958b\u59cb\u4e0d\u53d7\u63a7\u5236\u5730\u751f\u9577\u3002<\/p>\n<p class=\"p-cancertype\">\u6709\u5225\u65bc\u8f03\u5e38\u898b\u7684\u76ae\u819a\u9ed1\u8272\u7d20\u7624\uff0c\u9019\u7a2e\u773c\u90e8\u60e1\u6027\u816b\u7624\u4e3b\u8981\u5f71\u97ff\u773c\u775b\u7684\u4e2d\u9593\u8272\u7d20\u5c64\uff0c\u5373\u8461\u8404\u819c\uff0c\u7531\u8679\u819c\u3001\u776b\u72c0\u9ad4\u548c\u8109\u7db2\u7d44\u6210\u3002\u7531\u65bc\u65e9\u671f\u75c7\u72c0\u901a\u5e38\u4e0d\u986f\u8457\u6216\u5b8c\u5168\u6c92\u6709\u75c7\u72c0\uff0c\u56e0\u6b64\u9019\u7a2e\u764c\u75c7\u4e00\u958b\u59cb\u5f80\u5f80\u4e0d\u70ba\u4eba\u6240\u5bdf\u89ba\uff0c\u4f7f\u53ca\u6642\u8a3a\u65b7\u8b8a\u5f97\u8907\u96dc\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u751f\u7269\u57fa\u790e\u8207\u764c\u75c7\u4ee3\u8b1d<\/h3>\n<p class=\"p-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u8207\u5176\u4ed6\u60e1\u6027\u816b\u7624\u4e00\u6a23\uff0c\u90fd\u6703\u51fa\u73fe\u4ee5\u6c83\u4f2f\u683c\u6548\u61c9\u70ba\u7279\u5fb5\u7684\u65b0\u9673\u4ee3\u8b1d\u8b8a\u5316\u3002\u5728\u9019\u7a2e\u60c5\u6cc1\u4e0b\uff0c\u764c\u7d30\u80de\u975e\u5e38\u4f9d\u8cf4\u8461\u8404\u7cd6\u7684\u5438\u6536\uff0c\u6d88\u8017\u8461\u8404\u7cd6\u7684\u901f\u5ea6\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8\u51fa\u7d04 200 \u500d - \u5373\u4f7f\u5728\u6709\u5927\u91cf\u6c27\u6c23\u5b58\u5728\u7684\u60c5\u6cc1\u4e0b\u4e5f\u662f\u5982\u6b64\u3002\u9019\u7a2e\u65b0\u9673\u4ee3\u8b1d\u73fe\u8c61\u8b93\u7d30\u80de\u5feb\u901f\u6210\u9577\u548c\u589e\u6b96\uff0c\u7a81\u986f\u51fa\u5148\u9032\u6cbb\u7642\u6280\u8853\u53ef\u4ee5\u91dd\u5c0d\u7684\u660e\u986f\u5f31\u9ede\u3002<\/p>\n<p class=\"p-cancertype\">William Kaelin Jr.\u535a\u58eb\u3001Gregg Semenza \u535a\u58eb\u548c Peter Ratcliffe \u535a\u58eb\u6700\u8fd1\u7372\u5f97\u8afe\u8c9d\u723e\u734e\u7684\u7814\u7a76\uff0c\u52a0\u6df1\u4e86\u6211\u5011\u5c0d\u764c\u75c7\u65b0\u9673\u4ee3\u8b1d\u548c\u7d30\u80de\u5c0d\u7f3a\u6c27\u53cd\u61c9\u7684\u4e86\u89e3\uff0c\u70ba\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u63d0\u4f9b\u4e86\u65b0\u7684\u6cbb\u7642\u76ee\u6a19\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u6d41\u884c\u7387\u8207\u4eba\u53e3\u7d71\u8a08<\/h3>\n<p class=\"p-cancertype\">\u5728\u5168\u7403\u7bc4\u570d\u5167\uff0c\u773c\u5167\u9ed1\u8272\u7d20\u7624\u7d04\u4f54\u6240\u6709\u9ed1\u8272\u7d20\u7624\u7684 5-6%\uff0c\u6839\u64da WHO 2024 \u5e74\u7684\u4f30\u8a08\uff0c\u5168\u7403\u6bcf\u5e74\u7d04\u6709 2,500 \u500b\u65b0\u8a3a\u65b7\u75c5\u4f8b\u3002\u5118\u7ba1\u767c\u75c5\u7387\u76f8\u5c0d\u8f03\u4f4e\uff0c\u4f46\u7531\u65bc\u5177\u6709\u9ad8\u5ea6\u8f49\u79fb\u6f5b\u529b\uff0c\u5c24\u5176\u662f\u8f49\u79fb\u5230\u809d\u81df\uff0c\u56e0\u6b64\u53ca\u6642\u767c\u73fe\u4ecd\u7136\u975e\u5e38\u91cd\u8981\u3002<\/p>\n<p class=\"p-cancertype\">\u5728\u9999\u6e2f\u53ca\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u5730\u5340\uff0c\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u767c\u75c5\u7387\u8f03\u897f\u65b9\u4eba\u53e3\u70ba\u4f4e\uff0c\u6bcf\u5e74\u6bcf\u5341\u842c\u4eba\u4e2d\u7d04\u6709 0.3-0.5 \u500b\u75c5\u4f8b\u3002\u7136\u800c\uff0c\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3\u7684\u8cc7\u6599\u986f\u793a\uff0c\u8fd1\u5e74\u4f86\uff0c\u773c\u5167\u9ed1\u8272\u7d20\u7624\u7684\u767c\u751f\u7387\u9010\u6f38\u4e0a\u5347\uff0c\u9019\u7a81\u986f\u4e86\u63d0\u9ad8\u5730\u5340\u610f\u8b58\u3001\u76e3\u6e2c\u548c\u81e8\u5e8a\u6e96\u5099\u7684\u5fc5\u8981\u6027\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u5e74\u9f61\u5c64\uff1a\u767c\u75c5\u7387\u5728 55-70 \u6b72\u4e4b\u9593\u9054\u5230\u9ad8\u5cf0\uff0c\u4e3b\u8981\u8a3a\u65b7\u5c0d\u8c61\u70ba\u8001\u5e74\u4eba\u3002<\/li>\n<li>\u6027\u5225\u5206\u5e03\uff1a\u5168\u7403\u7537\u6027\u7684\u767c\u75c5\u7387\u7565\u9ad8\u65bc\u5973\u6027\uff0c\u9999\u6e2f\u7684\u8da8\u52e2\u8207\u6b64\u985e\u4f3c\u3002<\/li>\n<li>\u6587\u5316\u548c\u4eba\u7a2e\u56e0\u7d20\uff1a\u8207\u767d\u7a2e\u4eba\u76f8\u6bd4\uff0c\u4e9e\u6d32\u4eba\u7684\u767c\u75c5\u7387\u8f03\u4f4e\uff0c\u53ef\u80fd\u8207\u907a\u50b3\u548c\u74b0\u5883\u56e0\u7d20\u6709\u95dc\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u60c5\u7dd2\u548c\u8eab\u9ad4\u5f71\u97ff<\/h3>\n<p class=\"p-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u8a3a\u65b7\u5c0d\u60a3\u8005\u7684\u8eab\u5fc3\u5065\u5eb7\u90fd\u6709\u6df1\u9060\u7684\u5f71\u97ff\u3002\u5c31\u8eab\u9ad4\u800c\u8a00\uff0c\u9019\u7a2e\u764c\u75c7\u53ef\u80fd\u6703\u5f71\u97ff\u8996\u529b\uff0c\u5c0e\u81f4\u90e8\u5206\u6216\u5b8c\u5168\u5931\u660e\u3001\u773c\u90e8\u4e0d\u9069\u4ee5\u53ca\u65e5\u5e38\u751f\u6d3b\u6d3b\u52d5\u4e2d\u65b7\u3002\u5728\u60c5\u7dd2\u65b9\u9762\uff0c\u9019\u7a2e\u60e1\u6027\u816b\u7624\u7684\u4e0d\u78ba\u5b9a\u6027\u548c\u6f38\u9032\u6027\u5e38\u6703\u5f15\u767c\u7126\u616e\u3001\u6291\u9b31\u548c\u76f8\u7576\u5927\u7684\u5fc3\u7406\u56f0\u64fe\uff0c\u5927\u5927\u5f71\u97ff\u751f\u6d3b\u54c1\u8cea\u3002<\/p>\n<p class=\"p-cancertype\">\u5728 AllCancer\uff0c\u63d0\u4f9b\u9ad4\u8cbc\u7684\u591a\u9818\u57df\u652f\u63f4\uff0c\u4ee5\u53ca\u6700\u5148\u9032\u7684\u6cbb\u7642\u6280\u8853\uff0c\u626e\u6f14\u8457\u95dc\u9375\u7684\u89d2\u8272\u3002\u4ee4\u4eba\u9f13\u821e\u7684\u75c5\u60a3\u6545\u4e8b\uff0c\u4f8b\u5982 James \u5229\u7528\u6211\u5011\u5275\u65b0\u7684\u4ee3\u8b1d\u7642\u6cd5\u514b\u670d\u7b2c\u4e09\u671f\u773c\u5167\u9ed1\u8272\u7d20\u7624\u7684\u611f\u4eba\u65c5\u7a0b\uff0c\u70ba\u8a31\u591a\u4eba\u5e36\u4f86\u5e0c\u671b\u8207\u4fe1\u5fc3\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u75c7\u72c0\u548c\u81e8\u5e8a\u8868\u73fe<\/h3>\n<p class=\"p-cancertype\">\u65e9\u671f\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u901a\u5e38\u53ea\u6703\u51fa\u73fe\u6975\u5c11\u7684\u660e\u986f\u8eab\u9ad4\u75c7\u72c0\u3002\u7136\u800c\uff0c\u9010\u6f38\u5730\uff0c\u81e8\u5e8a\u8868\u73fe\u53ef\u80fd\u5305\u62ec<\/p>\n<ul class=\"p-cancertype\">\n<li>\u8996\u529b\u6a21\u7cca\u6216\u8996\u89ba\u6a21\u5f0f\u626d\u66f2\u3002<\/li>\n<li>\u51fa\u73fe\u6d6e\u9ede (floatingers) \u6216\u9583\u5149\u3002<\/li>\n<li>\u8679\u819c\u7684\u5f62\u72c0\u6216\u984f\u8272\u6539\u8b8a\u3002<\/li>\n<li>\u5468\u908a\u8996\u529b\u4e0b\u964d\u6216\u7a81\u7136\u5931\u53bb\u8996\u529b\u3002<\/li>\n<li>\u773c\u775b\u767c\u7d05\u6216\u6301\u7e8c\u523a\u6fc0\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u5728\u9ad8\u98a8\u96aa\u65cf\u7fa4\u4e2d\u5b9a\u671f\u9032\u884c\u773c\u79d1\u6aa2\u67e5\u53ef\u5927\u5e45\u63d0\u5347\u65e9\u671f\u767c\u73fe\u7387\uff0c\u5f9e\u6839\u672c\u4e0a\u6539\u5584\u9810\u5f8c\u60c5\u6cc1\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u6210\u56e0\u8207\u98a8\u96aa\u56e0\u7d20<\/h2>\n<h3 class=\"h3-cancertype\">\u907a\u50b3\u56e0\u7d20<\/h3>\n<p class=\"p-cancertype\">\u6709\u5e7e\u7a2e\u57fa\u56e0\u7a81\u8b8a\u548c\u907a\u50b3\u57fa\u56e0\u72c0\u6cc1\u5c0d\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u7684\u767c\u75c5\u6709\u5f88\u5927\u7684\u5f71\u97ff\u3002\u57fa\u56e0\u5716\u8b5c\u5206\u6790\u8d8a\u4f86\u8d8a\u591a\u5730\u986f\u793a GNAQ\u3001GNA11\u3001BAP1\u3001EIF1AX \u548c SF3B1 \u7684\u7a81\u8b8a\uff0c\u9019\u4e9b\u7a81\u8b8a\u8207\u816b\u7624\u7684\u4fb5\u8972\u6027\u548c\u5206\u4f48\u6709\u95dc\u3002<\/p>\n<p class=\"p-cancertype\">BAP1 \u57fa\u56e0\u8868\u9054\u7684\u55aa\u5931\u5c24\u5176\u7a81\u986f\u4e86\u8f49\u79fb\u6f5b\u529b\u7684\u589e\u52a0\u548c\u4e0d\u826f\u7684\u9810\u5f8c\u60c5\u6cc1\uff0c\u4fc3\u4f7f\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b James Allison \u535a\u58eb\u548c\u570b\u969b\u4ee3\u8b1d\u816b\u7624\u5b78\u5148\u9a45\u674e\u570b\u83ef\u535a\u58eb\u7b49\u7814\u7a76\u4eba\u54e1\u5229\u7528\u9019\u4e9b\u907a\u50b3\u5f31\u9ede\u5c0b\u6c42\u6a19\u9776\u6cbb\u7642\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u74b0\u5883\u548c\u751f\u6d3b\u65b9\u5f0f\u56e0\u7d20<\/h3>\n<p class=\"p-cancertype\">\u904e\u5ea6\u66b4\u9732\u65bc\u7d2b\u5916\u7dda (UV) \u8f3b\u5c04\u548c\u5ba4\u5167\u66ec\u9ed1\u53ef\u80fd\u6703\u589e\u52a0\u98a8\u96aa\uff0c\u5118\u7ba1\u8207\u76ae\u819a\u9ed1\u8272\u7d20\u7624\u76f8\u6bd4\uff0c\u773c\u8272\u7d20\u5c64\u9ed1\u8272\u7d20\u7624\u7684\u5177\u9ad4\u8b49\u64da\u4ecd\u7136\u8f03\u5f31\u3002\u5118\u7ba1\u5982\u6b64\uff0c\u5f9e\u9810\u9632\u7684\u89d2\u5ea6\u4f86\u770b\uff0c\u9650\u5236\u4e0d\u5fc5\u8981\u7684\u7d2b\u5916\u7dda\u66dd\u9732\u4ecd\u662f\u660e\u667a\u4e4b\u8209\u3002<\/p>\n<h4 class=\"h4-cancertype\">\u751f\u6d3b\u65b9\u5f0f\u7684\u8003\u91cf\uff1a<\/h4>\n<ul class=\"p-cancertype\">\n<li>\u6709\u8a18\u9304\u7684\u751f\u6d3b\u65b9\u5f0f\u5f71\u97ff\u6709\u9650\uff0c\u4f46\u900f\u904e\u5747\u8861\u98f2\u98df\u548c\u5b9a\u671f\u904b\u52d5\u7dad\u6301\u6574\u9ad4\u5065\u5eb7\u53ef\u964d\u4f4e\u4e00\u822c\u764c\u75c7\u98a8\u96aa\u3002<\/li>\n<li>\u80a5\u80d6\u3001\u9ad8\u8840\u58d3\u3001\u65b0\u9673\u4ee3\u8b1d\u5931\u8abf\uff0c\u7531\u65bc\u7d30\u80de\u5c64\u9762\u4e0a\u7684\u65b0\u9673\u4ee3\u8b1d\u8abf\u7bc0\u529f\u80fd\u53d7\u640d\uff0c\u53ef\u80fd\u8207\u764c\u75c7\u6613\u611f\u6027\u589e\u52a0\u9593\u63a5\u76f8\u95dc\u806f\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p class=\"p-cancertype\">\u764c\u75c7\u65b0\u9673\u4ee3\u8b1d\u7814\u7a76\u7684\u4e00\u500b\u91cd\u8981\u7279\u5fb5\u662f\u7d30\u80de\u65b0\u9673\u4ee3\u8b1d\u6a5f\u5236\u7684\u6539\u8b8a\u3002\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\u975e\u5e38\u4f9d\u8cf4\u8461\u8404\u7cd6\u548c\u7a40\u6c28\u9170\u80fa\u7b49\u7368\u7279\u7684\u4ee3\u8b1d\u5e95\u7269\uff0c\u5176\u4f7f\u7528\u91cf\u9060\u9ad8\u65bc\u5065\u5eb7\u7d30\u80de\uff0c\u901a\u5e38\u7528\u65bc\u7522\u751f ATP\u3001\u5408\u6210\u6838\u82f7\u9178\u548c\u7dad\u6301\u589e\u6b96\u7684\u751f\u7269\u5408\u6210\u9014\u5f91\u3002<\/p>\n<p class=\"p-cancertype\">\u56e0\u6b64\uff0c\u91dd\u5c0d\u9019\u4e9b\u65b0\u9673\u4ee3\u8b1d\u901a\u8def\u9032\u884c\u6cbb\u7642\u662f\u5f88\u6709\u5e0c\u671b\u7684\uff1bAllCancer \u7684\u8afe\u8c9d\u723e\u734e\u9748\u611f\u4f86\u6e90\u300c4D \u65b0\u9673\u4ee3\u8b1d\u6cbb\u7642\u300d\u7d50\u5408\u4e86\u9019\u4e9b\u539f\u5247\uff0c\u9078\u64c7\u6027\u5730\u91dd\u5c0d\u764c\u7d30\u80de\uff0c\u540c\u6642\u4fdd\u8b77\u5065\u5eb7\u7d44\u7e54\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u4e9e\u6d32\u7279\u6709\u98a8\u96aa\u53ca\u9999\u6e2f\u60c5\u6cc1<\/h3>\n<p class=\"p-cancertype\">\u96d6\u7136\u5728\u9999\u6e2f\u76f8\u5c0d\u4e0d\u5e38\u898b\uff0c\u4f46\u7531\u611f\u67d3\u548c\u767c\u708e\u5f15\u767c\u7684\u5176\u4ed6\u764c\u75c7\uff08\u5982\u4e59\u578b\u809d\u708e\u75c5\u6bd2\u5f15\u767c\u7684\u809d\u764c\u6216\u5e7d\u9580\u87ba\u65cb\u687f\u83cc\u5f15\u767c\u7684\u80c3\u764c\uff09\u5728\u4eba\u53e3\u4e2d\u7684\u7206\u767c\u63d0\u9ad8\u4e86\u516c\u773e\u5c0d\u5065\u5eb7\u7684\u95dc\u6ce8\uff0c\u4e26\u70ba\u8b66\u60d5\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7b49\u764c\u75c7\u63d0\u4f9b\u4e86\u7406\u64da\u3002<\/p>\n<p class=\"p-cancertype\">\u6211\u5011\u8207\u5168\u7403\u77e5\u540d\u7684\u7814\u7a76\u6a5f\u69cb\uff08\u5305\u62ec MD Anderson \u764c\u75c7\u4e2d\u5fc3\uff09\u5408\u4f5c\uff0c\u4e26\u8207\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u5efa\u7acb\u5925\u4f34\u95dc\u4fc2\uff0c\u4f7f\u6211\u5011\u80fd\u5920\u91dd\u5c0d\u9999\u6e2f\u548c\u9130\u8fd1\u5730\u5340\u7684\u4e9e\u6d32\u4eba\u53e3\uff0c\u63a1\u7528\u6700\u5148\u9032\u7684\u7814\u7a76\u65b9\u6cd5\u548c\u9810\u9632\u63aa\u65bd\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u75c7\u72c0<\/h2>\n<p class=\"p-cancertype\">\u53ca\u65e9\u8b58\u5225 <strong>\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/strong> \u986f\u8457\u6539\u5584\u60a3\u8005\u7684\u7642\u6548\u3002\u77ad\u89e3\u9019\u4e9b\u75c7\u72c0\u4e26\u53ca\u6642\u5c0b\u6c42\u91ab\u7642\u6307\u5c0e\u53ef\u4ee5\u6539\u8b8a\u751f\u547d\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u5e38\u898b\u75c7\u72c0\u5305\u62ec<\/h3>\n<ul class=\"p-cancertype\">\n<li>\u8996\u529b\u6a21\u7cca\u6216\u4e0d\u660e\u539f\u56e0\u7684\u8996\u529b\u4e2d\u65b7\u3002<\/li>\n<li>\u8996\u91ce\u4e2d\u6709\u6301\u7e8c\u6027\u7684\u9583\u720d\u6216\u6f02\u6d6e\u7269\u3002<\/li>\n<li>\u5468\u908a\u8996\u529b\u55aa\u5931\uff0c\u9010\u6f38\u6216\u7a81\u7136\u55aa\u5931\u3002<\/li>\n<li>\u8679\u819c\u4e0a\u6709\u660e\u986f\u7684\u9ed1\u6591\uff0c\u4e26\u9010\u6f38\u8b8a\u5927\u3002<\/li>\n<li>\u77b3\u5b54\u5f62\u72c0\u6216\u5927\u5c0f\u6539\u8b8a\uff0c\u901a\u5e38\u4e0d\u898f\u5247\u3002<\/li>\n<li>\u773c\u775b\u4e0d\u9069\u6216\u6709\u58d3\u8feb\u611f\uff08\u5c11\u898b\u4f46\u503c\u5f97\u6ce8\u610f\uff09\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u5404\u968e\u6bb5\u7684\u75c7\u72c0\u8b8a\u5316\uff1a<\/h3>\n<h4 class=\"h4-cancertype\">\u968e\u6bb5 1\uff1a<\/h4>\n<ul class=\"p-cancertype\">\n<li>\u8f15\u5fae\u7684\u8996\u529b\u8b8a\u5316\uff0c\u5982\u8f15\u5fae\u6a21\u7cca\u6216\u5fae\u5c0f\u7684\u6d6e\u9ede\u3002<\/li>\n<li>\u901a\u5e38\u7121\u75c7\u72c0\uff0c\u5e38\u5728\u4f8b\u884c\u773c\u79d1\u6aa2\u67e5\u6642\u767c\u73fe\u3002<\/li>\n<\/ul>\n<h4 class=\"h4-cancertype\">\u7b2c 2 \u968e\u6bb5\uff1a<\/h4>\n<ul class=\"p-cancertype\">\n<li>\u8996\u529b\u969c\u7919\u589e\u52a0<\/li>\n<li>\u5c0d\u5f37\u5149\u6216\u7729\u5149\u654f\u611f\u3002<\/li>\n<li>\u8996\u529b\u4e2d\u5ea6\u55aa\u5931\u6e05\u6670\u5ea6\uff0c\u5f71\u97ff\u65e5\u5e38\u6d3b\u52d5\u3002<\/li>\n<\/ul>\n<h4 class=\"h4-cancertype\">\u7b2c 3 \u968e\u6bb5\uff1a<\/h4>\n<ul class=\"p-cancertype\">\n<li>\u5468\u908a\u8996\u529b\u660e\u986f\u60e1\u5316\u3002<\/li>\n<li>\u5ee3\u6cdb\u7684\u773c\u5167\u58d3\u5347\u9ad8\u5c0e\u81f4\u9752\u5149\u773c\u3002<\/li>\n<li>\u56e0\u816b\u7624\u589e\u5927\u800c\u5f15\u8d77\u75bc\u75db\u6216\u660e\u986f\u4e0d\u9069\u3002<\/li>\n<\/ul>\n<h4 class=\"h4-cancertype\">\u7b2c 4 \u671f\uff08\u8f49\u79fb\u6027\u75be\u75c5\uff09\uff1a<\/h4>\n<ul class=\"p-cancertype\">\n<li>\u5168\u8eab\u75c7\u72c0\uff0c\u5982\u75b2\u5026\u3001\u9ad4\u91cd\u4e0b\u964d\u548c\u5168\u8eab\u4e0d\u9069\u3002<\/li>\n<li>\u8207\u8f49\u79fb\u90e8\u4f4d\u76f8\u95dc\u7684\u75c7\u72c0\u4e3b\u8981\u662f\u809d\u81df\u4e0d\u9069\u6216\u9ec3\u75b8\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u9019\u4e9b\u75c7\u72c0\u53cd\u6620\u4e86\u816b\u7624\u7684\u751f\u7269\u884c\u70ba\uff0c\u5c24\u5176\u662f\u5176\u4fb5\u8972\u6027\u548c\u6539\u8b8a\u773c\u775b\u7cbe\u5bc6\u5167\u90e8\u7d50\u69cb\u7684\u6f5b\u5728\u53ef\u80fd\u6027\u3002\u7531\u65bc\u764c\u7d30\u80de\u7684\u8461\u8404\u7cd6\u6d88\u8017\u91cf\u589e\u52a0\uff08\u6c83\u4f2f\u683c\u6548\u61c9\uff09\uff0c\u816b\u7624\u7684\u5feb\u901f\u589e\u6b96\u901a\u5e38\u6703\u52a0\u91cd\u8996\u529b\u969c\u7919\u3002\u56e0\u6b64\uff0c\u53ca\u65e9\u767c\u73fe\u9019\u4e9b\u75c7\u72c0\u4e26\u7acb\u5373\u5c0b\u6c42\u81e8\u5e8a\u8a55\u4f30\uff0c\u53ef\u4ee5\u986f\u8457\u6539\u5584\u9810\u5f8c\u3002 <a href=\"\/hk\/diagnostics\/\" class=\"p-cancertype\">\u7acb\u5373\u63a2\u7d22\u8a3a\u65b7\u65b9\u6cd5\u3002<\/a><\/p>\n<h2 class=\"h2-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u5206\u671f\u8207\u5b58\u6d3b\u7387<\/h2>\n<p class=\"p-cancertype\">\u7cbe\u78ba\u7684\u5206\u671f <strong>\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/strong> \u5728\u6c7a\u5b9a\u6700\u4f73\u6cbb\u7642\u8def\u5f91\u548c\u544a\u77e5\u60a3\u8005\u9810\u671f\u5b58\u6d3b\u7d50\u679c\u65b9\u9762\u81f3\u95dc\u91cd\u8981\u3002\u4ee5\u4e0b\u662f\u7d50\u69cb\u5316\u7684\u7d30\u5206\uff0c\u5f37\u8abf\u8207\u4e9e\u6d32\uff0c\u7279\u5225\u662f\u9999\u6e2f\u7684\u75c5\u60a3\u8cc7\u6599\u5eab\u76f8\u95dc\u7684\u7d71\u8a08\u8cc7\u6599\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u7b2c 1 \u671f - \u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/h3>\n<p class=\"p-cancertype\">\u7b2c\u4e00\u671f\u816b\u7624\u662f\u5c40\u90e8\u6027\u7684\uff0c\u800c\u4e14\u9ad4\u7a4d\u5f88\u5c0f\u3002\u4e00\u822c\u800c\u8a00\uff0c\u816b\u7624\u539a\u5ea6\u5c0f\u65bc 3 mm\uff0c\u4e26\u56b4\u683c\u9650\u5236\u5728\u8461\u8404\u819c\u7d44\u7e54\u5167\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u5c40\u9650\u65bc\u773c\u90e8\uff0c\u7121\u6dcb\u5df4\u6216\u9060\u7aef\u64f4\u6563\u3002<\/li>\n<li>\u624b\u8853\u3001\u5c40\u90e8\u8fd1\u8ddd\u6cbb\u7642\u6216\u8cea\u5b50\u675f\u5c04\u7dda\u80fd\u6709\u6548\u63a7\u5236\u3002<\/li>\n<li>\u9810\u5f8c\u6975\u4f73\uff0c\u6839\u64da\u6700\u8fd1\u7684\u9999\u6e2f\u81e8\u5e8a\u8cc7\u6599\uff082024\uff09\uff0c\u4e94\u5e74\u5167\u7684\u5b58\u6d3b\u7387\u9ad8\u65bc 90%\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 2 \u671f - \u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/h3>\n<p class=\"p-cancertype\">\u816b\u7624\u9ad4\u7a4d\u589e\u5927\u662f\u7b2c 2 \u671f\u7684\u7279\u5fb5\uff0c\u816b\u7624\u4ecd\u5c6c\u5c40\u90e8\u6027\uff0c\u4f46\u6709\u5f88\u5927\u7684\u98a8\u96aa\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u816b\u7624\u7684\u539a\u5ea6\u901a\u5e38\u5728 3 mm \u5230 8 mm \u4e4b\u9593\u3002<\/li>\n<li>\u81e8\u5e8a\u76e3\u63a7\u548c\u806f\u5408\u6cbb\u7642\uff08\u653e\u5c04\u7dda\u8207\u624b\u8853\uff09\u53ef\u63d0\u9ad8\u81e8\u5e8a\u7d50\u679c\u3002<\/li>\n<li>\u9999\u6e2f\u7684\u5b58\u6d3b\u7387\u8cc7\u6599\u986f\u793a\uff0c70-85% \u7684\u4e94\u5e74\u5b58\u6d3b\u7387\u5341\u5206\u7a69\u5065\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 3 \u671f - \u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/h3>\n<p class=\"p-cancertype\">\u7b2c 3 \u671f\u6a19\u8a8c\u8457\u986f\u8457\u7684\u9032\u5c55\u3001\u816b\u7624\u4fb5\u8972\u6027\u8d85\u51fa\u773c\u90e8\u7d50\u69cb\uff0c\u901a\u5e38\u6703\u5f71\u97ff\u773c\u7736\u7d44\u7e54\u6216\u51fa\u73fe\u6dcb\u5df4\u53d7\u7d2f\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u816b\u7624\u539a\u5ea6\u901a\u5e38\u9ad8\u65bc 8 mm\u3002<\/li>\n<li>\u53ef\u80fd\u9700\u8981\u5ee3\u6cdb\u7684\u4ecb\u5165\uff0c\u5305\u62ec\u773c\u7403\u6458\u9664\u8853 (enucleation)\u3001\u7d50\u5408\u653e\u5c04\u7dda\u3001\u514d\u75ab\u6cbb\u7642\u65b9\u6848\u3002<\/li>\n<li>\u8207\u65e9\u671f\u968e\u6bb5\u76f8\u6bd4\uff0c\u5b58\u6d3b\u7387\u524d\u666f\u986f\u8457\u964d\u4f4e\uff0c\u6700\u8fd1\u7684\u4e9e\u6d32\u8cc7\u6599\u986f\u793a\uff0c\u4e94\u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 50-70%\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 4 \u671f - \u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09<\/h3>\n<p class=\"p-cancertype\">\u7b2c 4 \u671f\u4ee3\u8868\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u901a\u5e38\u6703\u64f4\u6563\u81f3\u809d\u81df\u548c\u80ba\u90e8\u3002\u665a\u671f\u72c0\u614b\u9700\u8981\u5168\u9762\u7684\u7cfb\u7d71\u6cbb\u7642\u65b9\u6cd5\uff0c\u5305\u62ec\u5316\u7642\u3001\u514d\u75ab\u7642\u6cd5\u548c\u665a\u671f\u81e8\u5e8a\u8a66\u9a57\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u986f\u8457\u7684\u8f49\u79fb\u6027\u816b\u7624\u8ca0\u64d4\u901a\u5e38\u5305\u62ec\u809d\u81df\u3001\u80ba\u90e8\u53d7\u7d2f\u3002<\/li>\n<li>\u7531\u65bc\u65b0\u9673\u4ee3\u8b1d\u6cbb\u7642\u7684\u6297\u85e5\u6027\uff0c\u6cbb\u7642\u5177\u6709\u6311\u6230\u6027\uff0c\u9700\u8981\u5275\u65b0\u7684\u65b9\u5f0f\uff0c\u4f8b\u5982\u65b0\u9673\u4ee3\u8b1d\u816b\u7624\u6cbb\u7642\uff08\u5f37\u8abf\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b Allison \u548c Semenza \u7684\u6210\u529f\u6848\u4f8b\uff09\u3002<\/li>\n<li>\u5728\u9999\u6e2f\uff0c\u4e09\u5e74\u7684\u5b58\u6d3b\u7387\u7d04\u70ba 20-30%\uff0c\u4f46\u300c4D \u4ee3\u8b1d\u7642\u6cd5\u300d\u7b49\u5275\u65b0\u6280\u8853\u65e8\u5728\u5927\u5e45\u5ef6\u9577\u9810\u671f\u58fd\u547d\uff0c\u4e26\u5efa\u7acb\u6162\u6027\u75be\u75c5\u7ba1\u7406\u9014\u5f91\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u7531\u65bc\u6700\u5148\u9032\u7684\u7642\u6cd5\u8457\u91cd\u65bc\u816b\u7624\u65b0\u9673\u4ee3\u8b1d\u7684\u7279\u6b8a\u5f31\u9ede\uff0c\u7ba1\u7406\u7b2c 4 \u671f\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\u8d8a\u4f86\u8d8a\u591a\u5730\u5f9e\u6162\u6027\u75be\u75c5\u7ba1\u7406\u7684\u89d2\u5ea6\u4f86\u770b\u5f85\u3002\u5305\u62ec\u674e\u570b\u83ef\u535a\u58eb\u548c\u5289\u570b\u9f8d\u6559\u6388\u7b49\u65b0\u9673\u4ee3\u8b1d\u816b\u7624\u5b78\u5148\u9a45\u958b\u767c\u7684\u65b0\u65b9\u6cd5\uff0c\u5c55\u793a\u4e86\u6f5b\u5728\u7684\u8f49\u8b8a\u6027\u81e8\u5e8a\u7d50\u679c\u3002<\/p>\n<p class=\"p-cancertype\">\u764c\u75c7\u7684\u767c\u5c55\u548c\u5b58\u6d3b\u7387\u6578\u64da\uff0c\u7279\u5225\u662f\u9999\u6e2f\u764c\u75c7\u767b\u8a18\u518a\u7684\u6578\u64da\uff0c\u5f37\u8abf\u53ca\u6642\u8a3a\u65b7\u3001\u5373\u6642\u6cbb\u7642\u4ecb\u5165\u548c\u6301\u7e8c\u7d50\u679c\u4e4b\u9593\u7684\u5bc6\u5207\u95dc\u4fc2\u3002\u56e0\u6b64\uff0c\u5b9a\u671f\u9032\u884c\u5168\u9762\u6027\u7684\u773c\u79d1\u8a55\u4f30\u5c0d\u65bc\u53ca\u65e9\u767c\u73fe\u3001\u63d0\u9ad8\u5b58\u6d3b\u7387\u53ca\u6539\u5584\u75c5\u60a3\u7684\u751f\u6d3b\u54c1\u8cea\u4ecd\u662f\u975e\u5e38\u91cd\u8981\u7684\u3002 <a href=\"\/hk\/treatment-options\/\" class=\"p-cancertype\">\u7acb\u5373\u63a2\u7d22\u5148\u9032\u7684\u6cbb\u7642\u65b9\u6848\u3002<\/a><\/p>\n<h2 class=\"h2-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u7684\u6cbb\u7642\u65b9\u6848<\/h2>\n<h3 class=\"h3-cancertype\">\u6a19\u6e96\u6cbb\u7642\u9078\u9805<\/h3>\n<p class=\"p-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u7684\u6cbb\u7642\u6d89\u53ca\u5404\u7a2e\u56e0\u61c9\u75be\u75c5\u968e\u6bb5\u3001\u75c5\u60a3\u5065\u5eb7\u72c0\u6cc1\u548c\u907a\u50b3\u7279\u5fb5\u800c\u91cf\u8eab\u6253\u9020\u7684\u6cbb\u7642\u7b56\u7565\u3002\u9078\u64c7\u6b63\u78ba\u7684\u6cbb\u7642\u65b9\u6cd5\u81f3\u95dc\u91cd\u8981\uff0c\u5c24\u5176\u662f\u8003\u616e\u5230\u773c\u90e8\u7d44\u7e54\u7684\u8907\u96dc\u6027\u548c\u5fae\u5999\u6027\u3002<\/p>\n<h4 class=\"h4-cancertype\">\u624b\u8853\u4ecb\u5165<\/h4>\n<p class=\"p-cancertype\">\u4f5c\u70ba\u524d\u7dda\u6cbb\u7642\uff0c\u624b\u8853\u9078\u64c7\u63d0\u4f9b\u6f5b\u5728\u7684\u7642\u6548\uff0c\u5c24\u5176\u662f\u65e9\u671f\u60e1\u6027\u816b\u7624\u3002\u5e38\u898b\u7684\u624b\u8853\u65b9\u5f0f\u5305\u62ec<\/p>\n<ul>\n<li>\u525c\u9664\u8853\uff1a \u5207\u9664\u53d7\u5f71\u97ff\u7684\u773c\u775b\u4ee5\u9632\u6b62\u816b\u7624\u64f4\u6563\uff0c\u4e00\u822c\u9069\u7528\u65bc\u816b\u7624\u8f03\u5927\u6216\u8996\u529b\u56b4\u91cd\u53d7\u640d\u7684\u60c5\u6cc1\u3002<\/li>\n<li>\u5c40\u90e8\u816b\u7624\u5207\u9664\u8853\uff1a\u4fdd\u7559\u773c\u775b\u548c\u90e8\u5206\u8996\u529b\uff0c\u53ea\u9069\u7528\u65bc\u975e\u5e38\u5c40\u90e8\u7684\u75be\u75c5\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u5728\u9999\u6e2f\u53ca\u4e9e\u6d32\u5404\u5730\uff0c\u7531\u65bc\u5148\u9032\u7684\u773c\u90e8\u816b\u7624\u624b\u8853\u7d93\u9a57\u6709\u9650\uff0c\u56e0\u6b64\u624b\u8853\u5148\u4f8b\u90fd\u5f37\u8abf\u53ca\u65e9\u767c\u73fe\u3002<\/p>\n<h4 class=\"h4-cancertype\">\u653e\u5c04\u6cbb\u7642<\/h4>\n<p class=\"p-cancertype\">\u653e\u5c04\u6cbb\u7642\u662f\u624b\u8853\u7684\u66ff\u4ee3\u65b9\u6848\uff0c\u5c0d\u8f03\u5c0f\u7684\u816b\u7624\u5c24\u5176\u6709\u5e6b\u52a9\u3002\u9078\u9805\u5305\u62ec<\/p>\n<ul>\n<li>\u6591\u584a\u8fd1\u8ddd\u6cbb\u7642\uff1a\u5c40\u90e8\u653e\u5c04\u7dda\u76f4\u63a5\u91dd\u5c0d\u816b\u7624\uff0c\u800c\u4e0d\u50b7\u5bb3\u5468\u570d\u7d44\u7e54\u3002\u7531\u65bc\u5275\u50b7\u6975\u5c0f\uff0c\u56e0\u6b64\u88ab\u8a8d\u70ba\u662f\u6cbb\u7642\u773c\u5167\u9ed1\u8272\u7d20\u7624\u7684\u9ec3\u91d1\u6a19\u6e96\u3002<\/li>\n<li>\u8cea\u5b50\u675f\u653e\u5c04\u6cbb\u7642\uff1a\u5c07\u7cbe\u78ba\u7684\u9ad8\u80fd\u91cf\u8cea\u5b50\u9001\u81f3\u9ed1\u8272\u7d20\u7624\uff0c\u9650\u5236\u5c0d\u773c\u90e8\u7d44\u7e54\u7684\u9031\u908a\u50b7\u5bb3\uff0c\u4f46\u9019\u9700\u8981\u5c08\u9580\u7684\u8a2d\u5099\uff0c\u5728\u4e9e\u6d32\u901a\u5e38\u5f88\u5c11\u898b\u3002<\/li>\n<li>\u7acb\u9ad4\u5b9a\u5411\u653e\u5c04\u624b\u8853\uff1a\u53c8\u7a31\u70ba\u4f3d\u99ac\u5200\u6216 CyberKnife\uff0c\u53ef\u900f\u904e\u591a\u91cd\u805a\u675f\u63d0\u4f9b\u7cbe\u78ba\u7684\u816b\u7624\u5b9a\u4f4d\u3002<\/li>\n<\/ul>\n<h4 class=\"h4-cancertype\">\u5316\u5b78\u6cbb\u7642\u65b9\u6cd5<\/h4>\n<p class=\"p-cancertype\">\u5316\u5b78\u6cbb\u7642\u5c0d\u65bc\u5c40\u90e8\u6027\u773c\u5167\u9ed1\u8272\u7d20\u7624\u7684\u7642\u6548\u4ecd\u7136\u6709\u9650\uff0c\u4f46\u5c0d\u65bc\u8f49\u79fb\u6027\u75c5\u4f8b\u5247\u53ef\u63d0\u4f9b\u5168\u8eab\u6027\u7684\u75be\u75c5\u63a7\u5236\u3002\u5e38\u7528\u7684\u85e5\u7269\u5305\u62ec\u9054\u5361\u5df4\u55ea (dacarbazine) \u548c\u66ff\u83ab\u5511\u80fa (temozolomide)\uff0c\u4f46\u50b3\u7d71\u4e0a\u53cd\u61c9\u7387\u4e0d\u9ad8\u3002\u5316\u5b78\u6cbb\u7642\u5e38\u8207\u514d\u75ab\u6cbb\u7642\u7d50\u5408\uff0c\u4ee5\u52a0\u5f37\u816b\u7624\u7684\u53cd\u61c9\u3002<\/p>\n<h4 class=\"h4-cancertype\">\u6a19\u9776\u8207\u514d\u75ab\u6cbb\u7642<\/h4>\n<p class=\"p-cancertype\">\u5148\u9032\u7684\u6cbb\u7642\u65b9\u6cd5\u6b63\u88ab\u5ee3\u6cdb\u63a2\u7d22\uff1a<\/p>\n<ul>\n<li>\u514d\u75ab\u6aa2\u67e5\u9ede\u6291\u5236\u5291 (ICIs) \u5982 pembrolizumab \u6216 nivolumab\uff1a\u5c0d\u8f49\u79fb\u6027\u9ed1\u8272\u7d20\u7624\u6709\u6548\u3002\u65b0\u7a4e\u7684\u5ea6\u8eab\u8a02\u9020\u514d\u75ab\u7642\u6cd5\u5728\u9999\u6e2f\u9010\u6f38\u6210\u70ba\u500b\u4eba\u5316\u91ab\u7642\u7684\u4e3b\u6d41\u3002<\/li>\n<li>MEK \u6291\u5236\u5291 (\u4f8b\u5982\uff1aselumetinib)\uff1a\u7528\u65bc\u8655\u7406\u651c\u5e36\u57fa\u56e0\u7a81\u8b8a (\u5c24\u5176\u662f GNAQ \u548c GNA11\u7a81\u8b8a) \u7684\u8f49\u79fb\u6027\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\u7684\u524d\u666f\u770b\u597d\u7684\u6a19\u9776\u85e5\u7269\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u65b0\u8208\u4ee3\u8b1d\u6cbb\u7642<\/h3>\n<p class=\"p-cancertype\">\u96a8\u8457\u5c0d\u764c\u75c7\u4ee3\u8b1d\u9014\u5f91\u4e86\u89e3\u7684\u589e\u52a0\uff0c\u51fa\u73fe\u4e86\u76f4\u63a5\u91dd\u5c0d\u764c\u7d30\u80de\u4ee3\u8b1d\u7684\u65b0\u578b\u6cbb\u7642\u9014\u5f91\u3002\u9019\u4e9b\u65b9\u6cd5\u5305\u62ec<\/p>\n<ul>\n<li>\u963b\u65b7\u8461\u8404\u7cd6\u8f49\u904b\u9ad4 GLUT1\/GLUT3 \u901a\u8def\uff0c\u9650\u5236\u764c\u75c7\u589e\u6b96\u6240\u9700\u7684\u8461\u8404\u7cd6\uff0c\u5229\u7528\u4e3b\u8981\u5728\u9ed1\u8272\u7d20\u7624\u4e2d\u89c0\u5bdf\u5230\u7684 Warburg \u6548\u61c9\u3002<\/li>\n<li>\u9451\u65bc\u9ed1\u8272\u7d20\u7624\u7d30\u80de\u7684\u65b0\u9673\u4ee3\u8b1d\u9ad8\u5ea6\u4f9d\u8cf4\u7a40\u80fa\u4f86\u63d0\u4f9b\u80fd\u91cf\u548c\u751f\u9577\uff0c\u56e0\u6b64\u4ee5\u7a40\u80fa\u4f9d\u8cf4\u901a\u8def\u70ba\u76ee\u6a19\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">AllCancer \u8207 MD Anderson \u548c\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u7b49\u6a5f\u69cb\u7684\u7814\u7a76\u5408\u4f5c\uff0c\u5c07\u9019\u4e9b\u5c16\u7aef\u7684\u4ee3\u8b1d\u7642\u6cd5\u5217\u70ba\u512a\u5148\u9805\u76ee\uff0c\u53cd\u6620\u51fa\u8a72\u5730\u5340\u6b63\u5728\u671d\u5411\u500b\u4eba\u5316\u3001\u7cbe\u6e96\u816b\u7624\u8b77\u7406\u7684\u65b9\u5411\u767c\u5c55\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u500b\u4eba\u5316\u91ab\u7642\uff1a\u5411\u524d\u9081\u9032\u7684\u91cd\u8981\u4e00\u6b65<\/h3>\n<p class=\"p-cancertype\">\u8003\u616e\u5230\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u8907\u96dc\u7684\u57fa\u56e0\u5716\u8b5c\uff0c\u57fa\u56e0\u6e2c\u8a66\u548c\u816b\u7624\u5716\u8b5c\u5206\u6790\u4ecd\u7136\u662f\u4e0d\u53ef\u6216\u7f3a\u7684\uff1a<\/p>\n<ul>\n<li>\u57fa\u56e0\u6aa2\u6e2c\u53ef\u8fa8\u8b58\u7279\u5b9a\u7a81\u8b8a\uff0c\u4ee5\u6307\u5c0e\u5148\u9032\u7684\u6a19\u9776\u6cbb\u7642\u3002<\/li>\n<li>\u500b\u4eba\u5316\u7684\u7167\u8b77\u8a08\u756b\u53ef\u8abf\u6574\u75c5\u60a3\u7279\u5b9a\u7684\u907a\u50b3\u548c\u751f\u7406\u56e0\u7d20\uff0c\u5927\u5e45\u63d0\u5347\u6cbb\u7642\u6548\u679c\u548c\u75c5\u60a3\u7684\u751f\u6d3b\u54c1\u8cea\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u7136\u800c\uff0c\u8981\u5728\u9999\u6e2f\u548c\u66f4\u5ee3\u6cdb\u7684\u4e9e\u6d32\u5730\u5340\u5be6\u65bd\uff0c\u9700\u8981\u5efa\u7acb\u5168\u9762\u7684\u764c\u75c7\u8b77\u7406\u4e2d\u5fc3\uff0c\u4ee5\u89e3\u6c7a\u73fe\u6709\u57fa\u790e\u8a2d\u65bd\u7684\u9650\u5236\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u773c\u5167\u9ed1\u8272\u7d20\u7624\uff08\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\uff09\u50b3\u7d71\u7642\u6cd5\u7684\u9650\u5236<\/h2>\n<h3 class=\"h3-cancertype\">\u5316\u7642\u76f8\u95dc\u9650\u5236<\/h3>\n<p class=\"p-cancertype\">\u96d6\u7136\u5316\u7642\u85e5\u7269\u53ef\u4ee5\u66ab\u6642\u89e3\u6c7a\u8f49\u79fb\u6027\u64f4\u6563\u7684\u554f\u984c\uff0c\u4f46\u5927\u91cf\u7684\u6bd2\u6027\u6703\u6e1b\u4f4e\u6574\u9ad4\u7684\u7642\u6548\uff1a<\/p>\n<ul>\n<li>\u5728\u7d04 78% \u7684\u6cbb\u7642\u75c5\u60a3\u4e2d\u767c\u73fe\u9aa8\u9ad3\u6291\u5236\uff0c\u5c0e\u81f4\u56b4\u91cd\u7684\u4e2d\u6027\u7c92\u6e1b\u5c11\u75c7\u548c\u8ca7\u8840\u3002<\/li>\n<li>\u5fc3\u808c\u6bd2\u6027\u767c\u751f\u7387\u9ad8\u9054 23%\uff0c\u5c24\u5176\u662f\u96a8\u8457\u6cbb\u7642\u6642\u9593\u7684\u5ef6\u9577\u3002<\/li>\n<li>\u56b4\u91cd\u7684\u5641\u5fc3\u548c\u75b2\u52de\u6703\u5927\u5927\u964d\u4f4e\u751f\u6d3b\u54c1\u8cea\uff0c\u5c24\u5176\u662f\u4ee5\u4e9e\u88d4\u4eba\u53e3\u70ba\u4e3b\u7684\u8001\u5e74\u4eba\u7fa4\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u653e\u5c04\u6cbb\u7642\u7684\u4f75\u767c\u75c7<\/h3>\n<p class=\"p-cancertype\">\u5118\u7ba1\u6709\u7cbe\u78ba\u7684\u7784\u6e96\u6280\u8853\uff0c\u653e\u5c04\u6cbb\u7642\u4ecd\u6703\u5e36\u4f86\u76f8\u7576\u5927\u7684\u98a8\u96aa\uff1a<\/p>\n<ul>\n<li>\u8996\u7db2\u819c\u5074\u908a\u53d7\u640d\u53ef\u80fd\u6703\u5c0e\u81f4\u6162\u6027\u8996\u529b\u640d\u5bb3\u6216\u5931\u660e\uff0c\u5c24\u5176\u662f\u8f3b\u5c04\u6027\u8996\u7db2\u819c\u75c5\u8b8a\u3001\u7f3a\u8840\u6216\u767d\u5167\u969c\u7b49\u4f75\u767c\u75c7\u3002<\/li>\n<li>\u9762\u90e8\u795e\u7d93\u6216\u9871\u795e\u7d93\u53d7\u5230\u4e8c\u6b21\u7167\u5c04\u50b7\u5bb3\uff0c\u5c0e\u81f4\u611f\u89ba\u55aa\u5931\u3001\u9762\u90e8\u8b8a\u5f62\u6216\u529f\u80fd\u5931\u5e38\u3002<\/li>\n<li>\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u98a8\u96aa\u5347\u9ad8 (\u6839\u64da JAMA Oncology 2023\uff0c300% \u8f03\u9ad8)\uff0c\u5c24\u5176\u662f\u9700\u8981\u9577\u671f\u8ffd\u8e64\u7684\u5e74\u8f15\u75c5\u60a3\u66f4\u9700\u6ce8\u610f\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u624b\u8853\u4ecb\u5165\u7684\u98a8\u96aa\u8207\u9650\u5236<\/h3>\n<p class=\"p-cancertype\">\u525c\u9664\u816b\u7624\u6216\u5340\u57df\u816b\u7624\u5207\u9664\u7b49\u624b\u8853\u65b9\u6cd5\u96d6\u7136\u6709\u6cbb\u6108\u7684\u6f5b\u529b\uff0c\u4f46\u624b\u8853\u98a8\u96aa\u5f88\u5927\uff1a<\/p>\n<ul>\n<li>\u624b\u8853\u5f8c\u611f\u67d3\u3001\u8996\u7db2\u819c\u812b\u843d\u548c\u50b7\u53e3\u7652\u5408\u53d7\u640d\u7684\u98a8\u96aa\u589e\u52a0\u3002<\/li>\n<li>\u5fc3\u7406\u5275\u50b7\u8207\u7f8e\u5bb9\u554f\u984c\u3001\u9577\u671f\u773c\u90e8\u75bc\u75db\u6709\u95dc\uff0c\u4e26\u5c0d\u6574\u9ad4\u60c5\u7dd2\u9020\u6210\u91cd\u5927\u5f71\u97ff\u3002<\/li>\n<li>\u4e9e\u6d32\u5404\u91ab\u7642\u4fdd\u5065\u8a2d\u65bd\u7684\u624b\u8853\u80fd\u529b\u6709\u9650\uff0c\u9650\u5236\u4e86\u8a31\u591a\u75c5\u60a3\u7372\u5f97\u6700\u4f73\u7684\u624b\u8853\u89e3\u6c7a\u65b9\u6848\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u5c0d\u665a\u671f\u75be\u75c5\u7684\u7642\u6548\u6210\u7591<\/h3>\n<p class=\"p-cancertype\">\u50b3\u7d71\u65b9\u6cd5\u5728\u665a\u671f\u6216\u8f49\u79fb\u671f\u7684\u7642\u6548\u901a\u5e38\u6703\u964d\u4f4e\uff1a<\/p>\n<ul>\n<li>\u5ba2\u89c0\u56de\u61c9\u7387 <21% in late-stage melanomas, implying ineffective disease management in progressive conditions.<\/li>\n<li>\u6709\u9650\u7684\u6210\u529f\u90e8\u5206\u6b78\u56e0\u65bc\u764c\u7d30\u80de\u589e\u5f37\u7684\u65b0\u9673\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236\uff0c\u5305\u62ec DNA \u4fee\u5fa9\u9175\u7d20\u6d3b\u6027\u986f\u8457\u5347\u9ad8 (\u9ad8\u9054 400%)\uff0c\u8207\u50b3\u7d71\u7642\u6cd5\u76f8\u6297\u8861\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u9999\u6e2f\u53ca\u4e9e\u6d32\u5730\u5340\u91ab\u7642\u4fdd\u5065\u7684\u6311\u6230<\/h3>\n<p class=\"p-cancertype\">\u4e9e\u6d32\u7279\u6709\u7684\u6311\u6230\u52a0\u91cd\u4e86\u6cbb\u7642\u7684\u9650\u5236\uff1a<\/p>\n<ul>\n<li>\u773c\u79d1\u816b\u7624\u5c08\u79d1\u4e2d\u5fc3\u7684\u7a00\u5c11\u9650\u5236\u4e86\u5168\u9762\u7167\u8b77\u7684\u53d6\u5f97\u3002<\/li>\n<li>\u7531\u65bc\u6709\u9650\u7684\u5be6\u9a57\u5ba4\u53ef\u7528\u6027\u548c\u5f8c\u52e4\u969c\u7919\uff0c\u53ca\u6642\u3001\u5148\u9032\u7684\u5206\u5b50\u907a\u50b3\u6e2c\u8a66\u53d7\u5230\u9650\u5236\u3002<\/li>\n<li>\u6587\u5316\u4e0a\u5c0d\u65bc\u773c\u79d1\u624b\u8853\u7684\u7336\u8c6b\uff0c\u662f\u56e0\u70ba\u64d4\u5fc3\u624b\u8853\u5f8c\u7684\u5916\u89c0\u7f8e\u611f\u548c\u751f\u6d3b\u54c1\u8cea\u53d7\u5230\u5f71\u97ff\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u8981\u89e3\u6c7a\u9019\u4e9b\u9650\u5236\u56e0\u7d20\uff0c\u5c31\u5fc5\u9808\u4ee5\u653f\u7b56\u70ba\u5c0e\u5411\uff0c\u9032\u884c\u6709\u91dd\u5c0d\u6027\u7684\u6539\u5584\u3001\u570b\u969b\u5408\u4f5c\u7814\u7a76\uff0c\u4e26\u6295\u8cc7\u65bc\u91ab\u7642\u7167\u8b77\u8a2d\u65bd\uff0c\u4ee5\u5927\u5e45\u6539\u5584\u75c5\u60a3\u7684\u9810\u5f8c\u72c0\u6cc1\u53ca\u63d0\u5347\u4e00\u822c\u6c11\u773e\u7684\u91ab\u7642\u7167\u8b77\u7d20\u990a\u3002<\/p>\n<p class=\"p-cancertype\">\u6b78\u6839\u7d50\u67e2\uff0c\u8981\u6539\u5584\u91ab\u7642\u670d\u52d9\uff0c\u5c31\u5fc5\u9808\u57f9\u80b2\u4ee5\u75c5\u60a3\u70ba\u4e2d\u5fc3\u7684\u7d9c\u5408\u6027\u816b\u7624\u79d1\u5be6\u52d9\uff0c\u4ee5\u6709\u6548\u4e14\u5bcc\u540c\u60c5\u5fc3\u7684\u65b9\u5f0f\uff0c\u8655\u7406\u9999\u6e2f\u53ca\u6574\u500b\u4e9e\u6d32\u5730\u5340\u5728\u8655\u7406\u8461\u8404\u819c\u9ed1\u8272\u7d20\u7624\u6642\u6240\u56fa\u6709\u7684\u7368\u7279\u81e8\u5e8a\u3001\u793e\u6703\u5fc3\u7406\u53ca\u6587\u5316\u4e0a\u7684\u7d30\u5fae\u5dee\u7570\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>\u5728 AllCancer \u63a2\u7d22\u773c\u5167\u9ed1\u8272\u7d20\u7624 (Uveal Melanoma) \u7684\u75c7\u72c0\u3001\u5206\u671f\u548c\u9769\u547d\u6027\u7684 HK \u4ee3\u8b1d\u7642\u6cd5\u3002<\/p>","protected":false},"author":3,"featured_media":7380,"parent":0,"menu_order":0,"template":"","class_list":["post-7729","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type\/7729","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"author":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/users\/3"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media\/7380"}],"wp:attachment":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media?parent=7729"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}