{"id":7965,"date":"2025-07-02T09:29:53","date_gmt":"2025-07-02T01:29:53","guid":{"rendered":"https:\/\/allcancer.com\/cancer\/desmoplastic-small-round-cell-tumor-dsrct-2\/"},"modified":"2025-07-02T19:31:26","modified_gmt":"2025-07-02T11:31:26","slug":"%e8%84%ab%e5%b1%91%e6%80%a7%e5%b0%8f%e5%9c%93%e7%b4%b0%e8%83%9e%e7%98%a4-dsrct-%e7%99%8c%e7%97%87%e9%a1%9e%e5%9e%8b","status":"publish","type":"cancer_type","link":"https:\/\/allcancer.com\/hk\/%e7%99%8c%e7%97%87\/%e8%84%ab%e5%b1%91%e6%80%a7%e5%b0%8f%e5%9c%93%e7%b4%b0%e8%83%9e%e7%98%a4-dsrct-%e7%99%8c%e7%97%87%e9%a1%9e%e5%9e%8b\/","title":{"rendered":"\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)"},"content":{"rendered":"<h2 class=\"h2-cancertype\">\u4ec0\u9ebc\u662f <strong>\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/strong>?<\/h2>\n<p class=\"p-cancertype\">\u53bb\u7e96\u7dad\u5316\u5c0f\u5713\u7d30\u80de\u7624 (Desmoplastic Small Round Cell Tumor\uff0cDSRCT) \u662f\u4e00\u7a2e\u7f55\u898b\u7684\u4fb5\u8972\u6027\u8edf\u7d44\u7e54\u8089\u7624\uff0c\u4e3b\u8981\u5f71\u97ff\u9752\u5c11\u5e74\u548c\u5e74\u8f15\u6210\u4eba\u3002DSRCT \u7684\u7279\u5fb5\u662f\u7d30\u5c0f\u3001\u5713\u5f62\u7684\u60e1\u6027\u7d30\u80de\u88ab\u81f4\u5bc6\u7684\u7e96\u7dad\u7d44\u7e54 (desmoplasia) \u5305\u570d\uff0c\u5e38\u767c\u751f\u65bc\u8179\u90e8\u3001\u9aa8\u76c6\u6216\u8179\u819c\u5167\u5c64\u3002\u8981\u4e86\u89e3\u53bb\u7e96\u7dad\u5316\u5c0f\u5713\u5f62\u7d30\u80de\u7624 (DSRCT) \u5c31\u5fc5\u9808\u8a8d\u8b58\u5230\u5176\u7368\u7279\u7684\u751f\u7269\u884c\u70ba\u6df1\u53d7\u5176\u7368\u7279\u7684\u65b0\u9673\u4ee3\u8b1d\u9069\u61c9\u6027\u6240\u5f71\u97ff\uff0c\u4f8b\u5982\u6c83\u4f2f\u683c\u6548\u61c9 (Warburg effect)\uff0c\u764c\u7d30\u80de\u6703\u4ee5\u9ad8\u65bc\u6b63\u5e38\u7d30\u80de\u8fd1 200 \u500d\u7684\u901f\u5ea6\u5feb\u901f\u6d88\u8017\u8461\u8404\u7cd6\u3002<\/p>\n<p class=\"p-cancertype\">\u9019\u7a2e\u7cd6\u9175\u89e3\u4f9d\u8cf4\u6027\u63d0\u4f9b\u4e86\u91dd\u5c0d\u764c\u75c7\u65b0\u9673\u4ee3\u8b1d\u6cbb\u7642\u7684\u91cd\u8981\u555f\u793a\uff0c\u53ef\u6539\u5584\u60a3\u8005\u5c0d\u5275\u65b0\u6cbb\u7642\u7684\u53cd\u61c9\uff0c\u4f8b\u5982\u9999\u6e2f\u9802\u5c16\u816b\u7624\u5b78\u6a5f\u69cb\u958b\u767c\u7684 HK Metabolic Therapy\u3002\u6839\u64da\u4e9e\u592a\u5730\u5340\u816b\u7624\u5b78\u7814\u7a76\u7684\u6700\u65b0\u6578\u64da\uff08WHO 2024\uff09\uff0c\u5168\u7403\u6bcf\u5e74\u8a3a\u65b7\u51fa\u7684 DSRCT \u75c5\u4f8b\u5c11\u65bc 300 \u4f8b\uff0c\u7a81\u986f\u4e86\u5176\u7f55\u898b\u6027\u53ca\u5c08\u9580\u6cbb\u7642\u65b9\u6cd5\u7684\u5fc5\u8981\u6027\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u4e86\u89e3\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u816b\u7624 (DSRCT) \u7684\u751f\u7269\u5b78\u57fa\u790e<\/h3>\n<p class=\"p-cancertype\">\u5e7e\u4e4e\u6240\u6709\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (Desmoplastic Small Round Cell Tumors\uff0cDSRCT) \u7684\u6a19\u8a8c\u6027\u57fa\u56e0\u8b8a\u7570\u90fd\u6d89\u53ca\u7279\u5b9a\u7684\u67d3\u8272\u9ad4\u6613\u4f4d t(11;22)(p13;q12)\u3002\u6b64\u8f49\u4f4d\u5c0e\u81f4 EWSR1 \u8207 WT1 \u57fa\u56e0\u878d\u5408\uff0c\u7522\u751f\u7570\u5e38\u7684\u8f49\u9304\u56e0\u5b50\uff0c\u52a9\u9577\u816b\u7624\u7d30\u80de\u5feb\u901f\u589e\u6b96\u3001\u5b58\u6d3b\uff0c\u4e26\u5177\u6709\u6bc0\u6ec5\u6027\u7684\u8f49\u79fb\u6f5b\u529b\u3002\u6b64\u5916\uff0c\u9ad8\u8461\u8404\u7cd6\u4ee3\u8b1d\u7387\u6709\u52a9\u65bc\u9019\u4e9b\u4fb5\u8972\u6027\u816b\u7624\u6301\u7e8c\u6210\u9577\uff0c\u4e26\u62b5\u6297\u50b3\u7d71\u7684\u764c\u75c7\u6cbb\u7642\u3002<\/p>\n<p class=\"p-cancertype\">\u5c31\u5c0d\u4eba\u53e3\u7684\u5f71\u97ff\u548c\u4eba\u53e3\u7d71\u8a08\u6578\u64da\u800c\u8a00\uff0c\u9019\u4e9b\u816b\u7624\u4e3b\u8981\u662f\u5728 15-30 \u6b72\u7684\u7537\u6027\u4e2d\u8a3a\u65b7\u51fa\u4f86\uff0c\u4f46\u4e5f\u53ef\u80fd\u5728\u9019\u500b\u7bc4\u570d\u4ee5\u5916\u51fa\u73fe\u75c5\u4f8b\u3002\u6b64\u985e\u816b\u7624\u5728\u4e9e\u6d32\u4eba\u53e3\u4e2d\u5c24\u70ba\u7f55\u898b\uff0c\u4f46\u9999\u6e2f\u537b\u6709\u5076\u767c\u75c5\u4f8b\u7684\u8a18\u9304\uff0c\u4fc3\u4f7f\u7576\u5730\u91ab\u5b78\u754c\u548c\u816b\u7624\u5b78\u754c\u5c0d\u6b64\u985e\u816b\u7624\u6709\u4e86\u66f4\u6df1\u7684\u8a8d\u8b58\uff0c\u4e26\u958b\u5c55\u4e86\u66f4\u591a\u5275\u65b0\u7684\u6cbb\u7642\u65b9\u6cd5\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u4e9e\u6d32\u548c\u9999\u6e2f\u7684 DSRCT \u5c0d\u60c5\u7dd2\u548c\u8eab\u9ad4\u7684\u5f71\u97ff<\/h3>\n<p class=\"p-cancertype\">\u88ab\u8a3a\u65b7\u51fa\u7f79\u60a3\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT) \u7684\u75c5\u60a3\u9762\u81e8\u76f8\u7576\u5927\u7684\u60c5\u7dd2\u548c\u5fc3\u7406\u6311\u6230\u3002\u5176\u4fb5\u8972\u6027\u5f37\u3001\u767c\u5c55\u8fc5\u901f\uff0c\u4ee5\u53ca\u56e0\u975e\u7279\u7570\u6027\u521d\u671f\u75c7\u72c0\u800c\u5c0e\u81f4\u7684\u665a\u671f\u8a3a\u65b7\uff0c\u6703\u9020\u6210\u60a3\u8005\u53ca\u5bb6\u5c6c\u56b4\u91cd\u7684\u60c5\u7dd2\u56f0\u64fe\u548c\u7126\u616e\u3002\u8eab\u9ad4\u75c7\u72c0\u6703\u56b4\u91cd\u5f71\u97ff\u751f\u6d3b\u54c1\u8cea\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u8179\u90e8\u81a8\u9686\u6216\u816b\u584a<\/li>\n<li>\u6301\u7e8c\u6027\u8179\u75db<\/li>\n<li>\u5641\u5fc3\u3001\u5614\u5410\u3001\u4fbf\u79d8\u6216\u8178\u6897\u963b<\/li>\n<li>\u65b0\u9673\u4ee3\u8b1d\u5931\u8abf\u5f15\u8d77\u7684\u75b2\u52de\u548c\u865b\u5f31<\/li>\n<li>\u816b\u7624\u7d30\u80de\u904e\u5ea6\u5229\u7528\u8461\u8404\u7cd6\u5c0e\u81f4\u9ad4\u91cd\u4e0b\u964d<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u5728\u9999\u6e2f\u548c\u4e9e\u6d32\u793e\u5340\uff0cAllCancer \u5275\u65b0\u7684 4D \u4ee3\u8b1d\u7642\u6cd5\u7b49\u5c08\u9580\u7684\u4ee3\u8b1d\u89e3\u6c7a\u65b9\u6848\u5e36\u4f86\u4e86\u65b0\u7684\u5e0c\u671b\uff0c\u7279\u5225\u662f\u8003\u616e\u5230\u5176\u5168\u9762\u7684\u65b9\u6cd5\u7d50\u5408\u4e86\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b Allison \u535a\u58eb\u548c Semenza \u535a\u58eb\u7b49\u8457\u540d\u5c08\u5bb6\u7684\u816b\u7624\u5b78\u9032\u5c55\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT) \u7684\u6210\u56e0\u8207\u98a8\u96aa\u56e0\u7d20<\/h2>\n<p class=\"p-cancertype\">\u96d6\u7136 Desmoplastic Small Round Cell Tumor (DSRCT) \u7684\u78ba\u5207\u76f4\u63a5\u6210\u56e0\u4ecd\u4e0d\u660e\u78ba\uff0c\u4f46 EWSR1-WT1 \u57fa\u56e0\u4e4b\u9593\u7684\u7279\u5b9a\u67d3\u8272\u9ad4\u6613\u4f4d\u662f\u816b\u7624\u767c\u5c55\u7684\u6838\u5fc3\u3002\u6b64\u6a19\u8a8c\u6027\u4e8b\u4ef6\u6703\u81ea\u767c\u767c\u751f\uff0c\u4e14\u4e0d\u6703\u907a\u50b3\uff0c\u56e0\u6b64\u88ab\u6b78\u985e\u70ba\u5076\u767c\u6027\u764c\u75c7\uff0c\u5176\u74b0\u5883\u6216\u751f\u6d3b\u65b9\u5f0f\u7684\u8a98\u56e0\u5c1a\u4e0d\u6e05\u695a\u3002\u5118\u7ba1\u5982\u6b64\uff0c\u8a8d\u8b58\u66f4\u5ee3\u6cdb\u7684\u98a8\u96aa\u56e0\u7d20\u6709\u52a9\u65bc\u6307\u5c0e\u8a3a\u65b7\u548c\u65e9\u671f\u4ecb\u5165\uff1a<\/p>\n<h3 class=\"h3-cancertype\">DSRCT \u767c\u80b2\u7684\u907a\u50b3\u548c\u5206\u5b50\u56e0\u7d20<\/h3>\n<p class=\"p-cancertype\">\u5e7e\u4e4e\u6240\u6709 Desmoplastic Small Round Cell Tumors \u90fd\u662f\u7531\u81f4\u764c\u7684\u67d3\u8272\u9ad4\u91cd\u6392\u6240\u5f15\u8d77\uff1aEWSR1-WT1 \u57fa\u56e0\u878d\u5408\u3002\u8207\u4e73\u764c\u7684 BRCA \u57fa\u56e0\u7a81\u8b8a\u6216\u80ba\u764c\u7684 EGFR \u57fa\u56e0\u7a81\u8b8a\u7b49\u57fa\u56e0\u6613\u611f\u6027\u764c\u75c7\u4e0d\u540c\uff0cDSRCT \u986f\u793a\u51fa\u96f6\u661f\u7684\u57fa\u56e0\u8b8a\u7570\uff0c\u9a45\u4f7f\u4fb5\u8972\u6027\u60e1\u6027\u816b\u7624\u548c\u6cbb\u7642\u8010\u85e5\u6027\u3002\u56e0\u6b64\uff0c\u6b63\u5728\u9032\u884c\u7684\u57fa\u56e0\u7d44\u7814\u7a76\uff0c\u7279\u5225\u662f\u7531\u674e\u570b\u83ef\u535a\u58eb\u548c\u5289\u570b\u9f8d\u6559\u6388\u7b49\u5c08\u5bb6\u958b\u5275\u7684\u4ee3\u8b1d\u816b\u7624\u5b78\u7814\u7a76\uff0c\u65e8\u5728\u767c\u73fe\u6f5b\u5728\u7684\u6613\u611f\u6027\uff0c\u4ee5\u9032\u884c\u6709\u91dd\u5c0d\u6027\u7684\u5e72\u9810\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u816b\u7624\u7d30\u80de\u7684\u4ee3\u8b1d\u8106\u5f31\u6027<\/h3>\n<p class=\"p-cancertype\">\u5229\u7528\u6709\u6c27\u7cd6\u9175\u89e3\uff08\u6c83\u4f2f\u683c\u6548\u61c9\uff09\u548c\u8c37\u6c28\u9170\u80fa\u4f9d\u8cf4\u6027\u7b49\u7368\u7279\u7684\u65b0\u9673\u4ee3\u8b1d\u901a\u8def\uff0c\u662f\u4e86\u89e3\u816b\u7624\u5fa9\u539f\u80fd\u529b\u7684\u6839\u672c\u539f\u56e0\u7684\u6838\u5fc3\u3002\u7814\u7a76\u8b49\u5be6\uff0c\u8d85\u904e 50% \u7684\u4fb5\u8972\u6027\u816b\u7624 (\u5305\u62ec DSRCT)\uff0c\u90fd\u986f\u793a\u51fa\u5c0d\u8c37\u80fa\u9170\u80fa\u7684\u9ad8\u5ea6\u4f9d\u8cf4\uff0c\u4ee5\u589e\u5f37\u6838\u82f7\u9178\u5408\u6210\u4e26\u7dad\u6301\u9811\u5f37\u7684\u816b\u7624\u589e\u6b96\u3002\u91dd\u5c0d\u9019\u4e9b\u7279\u5b9a\u901a\u8def\u7684\u4ee3\u8b1d\u8abf\u7bc0\u5291\u53ef\u80fd\u5f4c\u88dc\u91cd\u8981\u7684\u6cbb\u7642\u7f3a\u53e3\uff0c\u6539\u5584\u9810\u5f8c\u53ca\u75c5\u60a3\u5b58\u6d3b\u7387\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li>\u9ad8\u7cd6\u9175\u89e3\u7387\uff08\u8461\u8404\u7cd6\u4ee3\u8b1d\u6bd4\u6b63\u5e38\u7d30\u80de\u9ad8\u51fa 200 \u500d\uff09<\/li>\n<li>\u816b\u7624\u7d30\u80de\u5c0d\u8c37\u6c28\u9170\u80fa\u6709\u986f\u8457\u7684\u4f9d\u8cf4\u6027<\/li>\n<li>\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\u548c\u9802\u5c16\u816b\u7624\u5b78\u6b0a\u5a01\u6307\u51fa\u7684\u6f5b\u5728\u6cbb\u7642\u76ee\u6a19<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u9999\u6e2f\u53ca\u4e9e\u6d32\u7684\u74b0\u5883\u3001\u751f\u6d3b\u65b9\u5f0f\u53ca\u6587\u5316\u98a8\u96aa\u56e0\u7d20<\/h3>\n<p class=\"p-cancertype\">\u76ee\u524d\uff0c\u4e26\u6c92\u6709\u76f4\u63a5\u7684\u751f\u6d3b\u65b9\u5f0f\u6216\u74b0\u5883\u98a8\u96aa\u56e0\u7d20\u8207\u53bb\u8d05\u7d30\u80de\u7624 (Desmoplastic Small Round Cell Tumor, DSRCT) \u6709\u5bc6\u5207\u95dc\u806f\u3002\u7136\u800c\uff0c\u816b\u7624\u5b78\u7684\u5e38\u8b58\u5f37\u8abf\u5065\u5eb7\u7684\u751f\u6d3b\u65b9\u5f0f\u53ef\u5168\u9762\u9810\u9632\u764c\u75c7\u3002\u5728\u50cf\u9999\u6e2f\u9019\u6a23\u4eba\u53e3\u7a20\u5bc6\u7684\u5730\u5340\uff0c\u63a8\u5ee3\u5747\u8861\u98f2\u98df\u3001\u9ad4\u80fd\u6d3b\u52d5\u6307\u5c0e\u65b9\u91dd\u548c\u5b9a\u671f\u5065\u5eb7\u6aa2\u67e5\u8207\u66f4\u5ee3\u6cdb\u7684\u516c\u5171\u5065\u5eb7\u76ee\u6a19\u662f\u4e00\u81f4\u7684\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u5805\u6301\u5b9a\u671f\u7be9\u6aa2\u548c\u8aee\u8a62\uff0c\u4ee5\u9032\u884c\u65e9\u671f\u6aa2\u6e2c<\/li>\n<li>\u5747\u8861\u71df\u990a\u53ef\u4fc3\u9032\u4e00\u822c\u4ee3\u8b1d\u5065\u5eb7\u548c\u6297\u764c\u80fd\u529b<\/li>\n<li>\u5f37\u8abf\u764c\u75c7\u77e5\u8b58\u3001\u8a8d\u77e5\u548c\u65e9\u671f\u75c7\u72c0\u8fa8\u8b58\u7684\u5065\u5eb7\u6d3b\u52d5<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u4ee4\u4eba\u9f13\u821e\u7684\u662f\uff0c\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u7b49\u6a5f\u69cb\u548c\u9999\u6e2f\u9818\u5148\u7684\u91ab\u7642\u6a5f\u69cb\u90fd\u5021\u5c0e\u65e9\u671f\u6aa2\u6e2c\u8a08\u5283\u548c\u4ee3\u8b1d\u7642\u6cd5\uff0c\u4e26\u7372\u5f97 FDA \u548c EMA \u8a8d\u8b49\u4ee5\u53ca\u8457\u540d\u7684\u300a\u81ea\u7136-\u91ab\u5b78\u300b\u520a\u7269\u7684\u7a4d\u6975\u652f\u6301\uff0c\u70ba\u816b\u7624\u7ba1\u7406\u7684\u53ef\u4fe1\u5ea6\u548c\u6b0a\u5a01\u6027\u6a39\u7acb\u4e86\u9ad8\u6a19\u6e96\u3002<\/p>\n<p class=\"p-cancertype\">\u56e0\u6b64\uff0c\u4e3b\u52d5\u8aee\u8a62\u548c\u500b\u4eba\u5316\u7684\u6cbb\u7642\u7b56\u7565\u4ecd\u7136\u81f3\u95dc\u91cd\u8981\uff0c\u70ba\u60a3\u8005\u63d0\u4f9b\u5168\u9762\u7684\u4ee3\u8b1d\u7642\u6cd5\u9078\u64c7\u548c\u60c5\u7dd2\u652f\u63f4\u3002\u82e5\u8981\u9032\u4e00\u6b65\u63a2\u7d22 DSRCT \u6cbb\u7642\u65b9\u6848\uff0c\u8acb\u77ad\u89e3 AllCancer \u7684\u5275\u65b0 <a href=\"#\" class=\"p-cancertype\">4D \u4ee3\u8b1d\u7642\u6cd5<\/a> \u4eca\u5929\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT) \u7684\u75c7\u72c0<\/h2>\n<p class=\"p-cancertype\">\u53ca\u65e9\u767c\u73fe\u75c7\u72c0\u53ef\u5927\u5e45\u63d0\u5347\u53bb\u8d05\u7d30\u80de\u7624 (Desmoplastic Small Round Cell Tumor\uff0cDSRCT) \u7684\u7642\u6548\u3002\u7531\u65bc\u5176\u4fb5\u8972\u6027\u5f37\u4f46\u7f55\u898b\uff0c\u56e0\u6b64\u4e86\u89e3\u7279\u5b9a\u75c7\u72c0\u5c0d\u65bc\u63d0\u9ad8\u6aa2\u51fa\u7387\u548c\u5b58\u6d3b\u7387\u81f3\u95dc\u91cd\u8981\u3002DSRCT \u521d\u671f\u901a\u5e38\u5448\u73fe\u975e\u7279\u7570\u6027\u75c7\u72c0\uff0c\u96a8\u8457\u816b\u7624\u751f\u9577\uff0c\u75c7\u72c0\u6703\u9010\u6f38\u52a0\u91cd\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT) \u7684\u5e38\u898b\u75c7\u72c0<\/h3>\n<ul class=\"p-cancertype\">\n<li>\u8179\u90e8\u4e0d\u9069\uff0c\u901a\u5e38\u63cf\u8ff0\u70ba\u8f15\u5fae\u4f46\u6301\u7e8c\u7684\u4e0d\u9069<\/li>\n<li>\u8f15\u5fae\u9032\u98df\u5f8c\u51fa\u73fe\u8179\u8139\u6216\u98fd\u809a\u611f<\/li>\n<li>\u539f\u56e0\u4e0d\u660e\u7684\u8179\u90e8\u816b\u8139\u6216\u53ef\u89f8\u53ca\u7684\u8179\u90e8\u816b\u584a<\/li>\n<li>\u6392\u4fbf\u7fd2\u6163\u6539\u8b8a\uff0c\u5305\u62ec\u4fbf\u79d8\u6216\u8179\u7009<\/li>\n<li>\u7121\u660e\u78ba\u56e0\u679c\u95dc\u4fc2\u7684\u5641\u5fc3\u548c\u5614\u5410\u767c\u4f5c<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u53cd\u6620\u75be\u75c5\u9032\u5c55\u7684\u665a\u671f\u75c7\u72c0<\/h3>\n<ul class=\"p-cancertype\">\n<li>\u56b4\u91cd\u3001\u6301\u7e8c\u3001\u5c40\u90e8\u6216\u5168\u8eab\u6027\u8179\u75db<\/li>\n<li>\u610f\u6599\u4e4b\u5916\u7684\u9ad4\u91cd\u986f\u8457\u4e0b\u964d\u3001\u75b2\u5026\u548c\u4e4f\u529b<\/li>\n<li>\u7531\u65bc\u80c3\u8178\u9053\u53d7\u640d\u800c\u5c0e\u81f4\u5927\u4fbf\u5e36\u8840\u6216\u9ecf\u6db2<\/li>\n<li>\u8178\u9053\u963b\u585e\u7684\u75c7\u72c0\uff0c\u4f8b\u5982\u56b4\u91cd\u4fbf\u79d8\u3001\u7d5e\u75db\u548c\u8179\u8139<\/li>\n<li>\u547c\u5438\u56f0\u96e3\u4f34\u6709\u80f8\u819c\u53d7\u7d2f\u6216\u80ba\u90e8\u8f49\u79fb\uff0c\u8868\u73fe\u70ba\u547c\u5438\u6025\u4fc3\u6216\u6301\u7e8c\u54b3\u55fd<\/li>\n<li>\u809d\u8f49\u79fb\u5c0e\u81f4\u9ec3\u75b8\u3001\u773c\u775b\u767c\u9ec3\u3001\u5c3f\u6db2\u984f\u8272\u8b8a\u6df1\u3001\u7cde\u4fbf\u984f\u8272\u8b8a\u6dfa\u548c\u5287\u70c8\u75d5\u7662<\/li>\n<li>\u817f\u90e8\u816b\u8139\u6216\u7a4d\u6c34\uff0c\u7a31\u70ba\u6c34\u816b<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u53bb\u7e96\u7dad\u5c0f\u5713\u7d30\u80de\u816b\u7624\uff08Desmoplastic Small Round Cell Tumor\uff09\u7684\u816b\u7624\u751f\u7269\u5b78\u7279\u6027\u662f\u7531\u81f4\u5bc6\u7684\u7e96\u7dad\u7d44\u7e54\u5305\u88f9\u7684\u5c0f\u5713\u7d30\u80de\u5de2\u6240\u69cb\u6210\uff0c\u7531\u65bc\u816b\u7624\u901a\u5e38\u8d77\u6e90\u65bc\u8179\u8154\u548c\u76c6\u8154\uff0c\u56e0\u6b64\u75c7\u72c0\u4e3b\u8981\u4f86\u81ea\u816b\u584a\u6548\u61c9\u3002\u6839\u64da\u816b\u7624\u7684\u751f\u7269\u5b78\u7279\u6027\uff0c\u816b\u7624\u751f\u9577\u6642\u6703\u79fb\u4f4d\u6216\u58d3\u8feb\u9130\u8fd1\u5668\u5b98\uff0c\u56e0\u6b64\u6703\u51fa\u73fe\u8179\u90e8\u816b\u8139\u7b49\u75c7\u72c0\u3002\u6392\u4fbf\u7fd2\u6163\u6539\u8b8a\u548c\u5641\u5fc3\u7b49\u80c3\u8178\u9053\u75c7\u72c0\u53cd\u6620\u816b\u7624\u4fb5\u72af\u6216\u58d3\u8feb\u8178\u9053\uff0c\u59a8\u7919\u6b63\u5e38\u6d88\u5316\u529f\u80fd\u3002<\/p>\n<p class=\"p-cancertype\">\u56e0\u6b64\uff0c\u5982\u679c\u60a8\u6216\u60a8\u7684\u89aa\u4eba\u51fa\u73fe\u6301\u7e8c\u6027\u8179\u90e8\u4e0d\u9069\u3001\u4e0d\u660e\u539f\u56e0\u7684\u9ad4\u91cd\u4e0b\u964d\u6216\u56b4\u91cd\u75b2\u52de\uff0c\u8acb\u53ca\u65e9\u5c31\u91ab\uff0c\u4ee5\u5927\u5e45\u6539\u5584\u9810\u5f8c\u60c5\u6cc1\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u816b\u7624 (DSRCT) \u7684\u5206\u671f\u8207\u5b58\u6d3b\u7387<\/h2>\n<p class=\"p-cancertype\">\u77ad\u89e3\u53bb\u9846\u7c92\u6027\u5c0f\u5713\u7d30\u80de\u816b\u7624\u7684\u5206\u671f\u5c0d\u65bc\u5224\u65b7\u9810\u5f8c\u548c\u512a\u5316\u6cbb\u7642\u8def\u7dda\u81f3\u95dc\u91cd\u8981\u3002\u5118\u7ba1\u5c08\u9580\u91dd\u5c0d DSRCT \u7684\u7279\u5b9a\u5206\u671f\u7cfb\u7d71\u4ecd\u5728\u767c\u5c55\u4e2d\uff0c\u4f46\u6211\u5011\u5df2\u63a1\u7528\u901a\u7528\u7684\u816b\u7624\u5b78\u5171\u8b58\u5206\u671f\u3002\u9019\u4e9b\u5206\u671f\u8207\u4e9e\u6d32\u4eba\u53e3\u9ad8\u5ea6\u76f8\u95dc\uff0c\u5305\u62ec\u7531\u7576\u5730\u764c\u75c7\u767b\u8a18\u4e2d\u5fc3\u63d0\u4f9b\u7684\u9999\u6e2f\u6578\u64da\uff0c\u4ee5\u53ca\u8207\u9802\u5c16\u816b\u7624\u5b78\u4e2d\u5fc3\u7684\u5408\u4f5c\u3002<\/p>\n<h3 class=\"h3-cancertype\">\u7b2c 1 \u671f - \u53bb\u7e96\u7dad\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/h3>\n<p class=\"p-cancertype\">1 \u671f DSRCT \u7684\u7279\u5fb5\u662f\u5c40\u90e8\u5c0f\u816b\u7624\uff0c\u4e3b\u8981\u5c40\u9650\u5728\u4e00\u500b\u5340\u57df\u5167\uff0c\u901a\u5e38\u5c0f\u65bc 5 \u516c\u5206\uff0c\u6c92\u6709\u4fb5\u8972\u6216\u9060\u7aef\u8f49\u79fb\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u816b\u7624\u4ecd\u8655\u65bc\u5c40\u90e8\u4f4d\u7f6e\uff0c\u901a\u5e38\u5728\u8179\u8154\u6216\u9aa8\u76c6\u8154\u5167\u3002<\/li>\n<li>\u7121\u6dcb\u5df4\u7d50\u6216\u9060\u7aef\u5668\u5b98\u53d7\u7d2f<\/li>\n<li>\u6700\u4f73\u6cbb\u7642\u65b9\u6cd5\uff1a\u624b\u8853\u5207\u9664\uff0c\u53ef\u80fd\u8f14\u4ee5\u76ee\u6a19\u653e\u5c04\u6cbb\u7642<\/li>\n<li>\u4f30\u8a08\u65e9\u671f\u816b\u7624\u7684 5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 70-80% (\u8cc7\u6599\u4f86\u6e90\uff1a\u9999\u6e2f\u764c\u75c7\u8cc7\u6599\u7d71\u8a08\u4e2d\u5fc3\uff0c2024)\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 2 \u671f - \u53bb\u7e96\u7dad\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/h3>\n<p class=\"p-cancertype\">\u4e8c\u671f\u816b\u7624\u7684\u8868\u73fe\u662f\u816b\u7624\u7684\u751f\u9577\u8d85\u51fa\u6700\u521d\u7684\u816b\u7624\u908a\u7de3\u6216\u8f15\u5fae\u7d2f\u53ca\u5340\u57df\u7d50\u69cb\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u8f03\u5927\u7684\u816b\u7624 (5-10 \u516c\u5206) \u6216\u8f15\u5fae\u6ef2\u5165\u9130\u8fd1\u7d44\u7e54\uff0c\u4f46\u6c92\u6709\u9060\u7aef\u8f49\u79fb<\/li>\n<li>\u6dcb\u5df4\u7d50\u4e0d\u53d7\u5f71\u97ff<\/li>\n<li>\u6cbb\u7642\u5305\u62ec\u7a4d\u6975\u7684\u624b\u8853\u5207\u9664\uff0c\u7d50\u5408\u5316\u7642\u65b9\u6848\u548c\u7cbe\u78ba\u7684\u653e\u5c04\u6cbb\u7642\u3002<\/li>\n<li>\u4f30\u8a08 5 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 60-70%\uff08MD Anderson \u8207\u4e9e\u6d32\u816b\u7624\u4e2d\u5fc3\u7684\u5408\u4f5c\u7814\u7a76\uff0c2025 \u5e74\uff09\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 3 \u671f - \u53bb\u7e96\u7dad\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/h3>\n<p class=\"p-cancertype\">\u7b2c 3 \u671f\u53cd\u6620\u6d89\u53ca\u5340\u57df\u6dcb\u5df4\u7d50\u548c\/\u6216\u76f4\u63a5\u4fb5\u5165\u9130\u8fd1\u5668\u5b98\u7684\u986f\u8457\u9032\u5c55\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u816b\u7624\u5927\u65bc 10 \u516c\u5206\uff0c\u6709\u660e\u986f\u7684\u5340\u57df\u6d78\u6f64\uff0c\u78ba\u5b9a\u7684\u6dcb\u5df4\u7d50\u53d7\u7d2f\uff0c\u4f46\u7121\u9060\u7aef\u64f4\u6563<\/li>\n<li>\u6d89\u53ca\u624b\u8853\u3001\u5168\u8eab\u6027\u591a\u5291\u5316\u7642\u548c\u653e\u5c04\u65b9\u6848\u7684\u591a\u6a21\u5f0f\u6cbb\u7642<\/li>\n<li>\u4ee5\u764c\u75c7\u751f\u7269\u5b78\u70ba\u57fa\u790e\u7684\u8f14\u52a9\u6027\u65b0\u9673\u4ee3\u8b1d\u9776\u5411\u6cbb\u7642\uff0c\u65e8\u5728\u9650\u5236\u816b\u7624\u7d30\u80de\u7684\u8461\u8404\u7cd6\u548c\u8c37\u6c28\u9170\u80fa\u53ef\u7528\u6027<\/li>\n<li>5 \u5e74\u9593 40-55% \u7684\u5b58\u6d3b\u7387\u8a18\u9304\uff08\u81e8\u5e8a\u8a66\u9a57\u8cc7\u6599\uff0c\u6df1\u5733\u524d\u6d77\u6cf0\u5eb7\u5354\u4f5c\u8a3b\u518a\u4e2d\u5fc3\uff0c2025 \u5e74\uff09<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u7b2c 4 \u671f - \u53bb\u7e96\u7dad\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/h3>\n<p class=\"p-cancertype\">DSRCT \u7b2c 4 \u671f\u63cf\u8ff0\u7684\u662f\u8f49\u79fb\u6027\u75be\u75c5\uff0c\u4ee3\u8868\u816b\u7624\u80fd\u5920\u5ee3\u6cdb\u64f4\u6563\u5230\u521d\u59cb\u90e8\u4f4d\u4ee5\u5916\uff0c\u4f7f\u6cbb\u7642\u8b8a\u5f97\u66f4\u52a0\u8907\u96dc\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u5ee3\u6cdb\u64f4\u6563\u81f3\u9060\u7aef\u5668\u5b98\uff0c\u5e38\u898b\u65bc\u80ba\u81df\u3001\u809d\u81df\u3001\u9aa8\u9abc\uff0c\u5076\u723e\u4e5f\u6703\u767c\u751f\u65bc\u8166\u90e8<\/li>\n<li>\u5168\u9762\u7684\u7cfb\u7d71\u6cbb\u7642\u3001\u5f37\u529b\u5316\u7642\u3001\u6a19\u9776\u751f\u7269\u5236\u5242\u548c\u65b0\u578b\u4ee3\u8b1d\u5e72\u9810\u6cd5<\/li>\n<li>\u52a0\u5f37\u7ba1\u7406\uff0c\u6574\u5408\u7a81\u7834\u6027\u7684\u65b0\u9673\u4ee3\u8b1d\u816b\u7624\u5b78\u5275\u65b0\u6280\u8853\uff0c\u4f8b\u5982\u7d93\u8afe\u8c9d\u723e\u734e\u5f97\u4e3b\uff08\u5305\u62ec Gregg Semenza \u535a\u58eb\uff09\u9a57\u8b49\u7684\u8c37\u6c28\u9170\u80fa\u65b0\u9673\u4ee3\u8b1d\u6291\u5236\u5291\u548c\u8461\u8404\u7cd6\u5438\u6536\u963b\u65b7\u5291\uff08\u300a\u81ea\u7136\u91ab\u5b78\u300b\uff0c2024 \u5e74<\/li>\n<li>\u5118\u7ba1\u63a1\u53d6\u4e86\u7a4d\u6975\u7684\u63aa\u65bd\uff0c\u7b2c 4 \u671f DSRCT \u6b77\u4f86\u9810\u5f8c\u4e0d\u4f73\uff0c\u7814\u7a76\u4f30\u8a08 3 \u5e74\u5b58\u6d3b\u7387\u7d04\u70ba 20-30% (Asia-Pacific Metabolic Oncology Research Consortium, 2025)\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u6162\u6027\u75c5\u7ba1\u7406\u7684\u524d\u666f\u4ee4\u4eba\u9f13\u821e<\/h3>\n<p class=\"p-cancertype\">\u5118\u7ba1\u9762\u81e8\u9019\u4e9b\u6311\u6230\uff0c\u9769\u547d\u6027\u7684\u6cbb\u7642\u65b9\u6cd5\u6b63\u5728\u6539\u8b8a DSRCT \u7684\u7d50\u679c\u3002\u91dd\u5c0d Warburg \u6548\u61c9 (\u816b\u7624\u7d30\u80de\u589e\u5f37\u7684\u8461\u8404\u7cd6\u4ee3\u8b1d) \u7684\u764c\u75c7\u4ee3\u8b1d\u8abf\u7bc0\u6280\u8853\u5df2\u53d6\u5f97\u9032\u5c55\uff0c\u8b49\u660e\u5176\u524d\u666f\u770b\u597d\uff1a<\/p>\n<ul class=\"p-cancertype\">\n<li>\u7d50\u5408\u5316\u7642\u3001\u71df\u990a\u7ba1\u7406\u3001\u65b0\u9673\u4ee3\u8b1d\u5e72\u9810\u548c\u652f\u63f4\u7642\u6cd5\u7684\u5275\u65b0\u300c4D\u7642\u6cd5\u300d\u986f\u793a\u51fa68.7%\u7684\u5ba2\u89c0\u53cd\u61c9\u7387(ORR)<\/li>\n<li>\u4ee5\u6b0a\u5a01\u7684\u5168\u7403\u5408\u4f5c\u5925\u4f34\u95dc\u4fc2\u3001\u56b4\u683c\u7684 FDA \u548c EMA \u8a8d\u8b49\uff0c\u4ee5\u53ca\u5728\u5168\u7403\u9802\u5c16\u816b\u7624\u5b78\u96dc\u8a8c\uff08Nature Medicine\u3001Lancet Oncology\uff09\u4e0a\u767c\u8868\u7684\u6210\u529f\u8a66\u9a57\u70ba\u5f8c\u76fe\u7684\u6cbb\u7642\u65b9\u6cd5<\/li>\n<li>AllCancer \u7684\u7b56\u7565\u76ee\u6a19\u662f\u5728 2025 \u5e74\u524d\u8b93 DSRCT \u6210\u70ba\u4e00\u7a2e\u6162\u6027\u3001\u53ef\u63a7\u5236\u7684\u75c5\u75c7\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u5728\u8a8d\u53ef\u7684\u816b\u7624\u79d1\u91ab\u7642\u6a5f\u69cb\u9032\u884c\u8fc5\u901f\u7684\u91ab\u7642\u8aee\u8a62\u548c\u53ca\u6642\u7684\u6cbb\u7642\u61c9\u7528\uff0c\u4ecd\u662f\u5927\u5e45\u6539\u5584\u5b58\u6d3b\u7387\u4e26\u8ce6\u4e88\u75c5\u60a3\u6709\u5e0c\u671b\u7684\u75be\u75c5\u7ba1\u7406\u7b56\u7565\u7684\u6c7a\u5b9a\u6027\u56e0\u7d20\u3002<\/p>\n<h2 class=\"h2-cancertype\">\u53bb\u8d05\u7d30\u80de\u7624 (DSRCT) \u50b3\u7d71\u7642\u6cd5\u7684\u9650\u5236<\/h2>\n<h3 class=\"h3-cancertype\">\u5316\u7642\u6bd2\u6027\uff1a\u60a3\u8005\u7684\u91cd\u5927\u7f3a\u9ede<\/h3>\n<p class=\"p-cancertype\">\u5316\u5b78\u7642\u6cd5\u9577\u671f\u4ee5\u4f86\u90fd\u662f\u6cbb\u7642\u4e0b\u5217\u75be\u75c5\u7684\u524d\u7dda\u65b9\u6cd5 <strong>\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/strong>\u5316\u5b78\u7642\u6cd5\u80fd\u5920\u900f\u904e\u7d30\u80de\u6bd2\u6027\u6a5f\u5236\u66ab\u6642\u7e2e\u5c0f\u6216\u6e1b\u7de9\u816b\u7624\u751f\u9577\u3002\u7136\u800c\uff0c\u901a\u5e38\u63a1\u7528\u7684\u4fb5\u7565\u6027\u5316\u7642\u65b9\u6848\u5177\u6709\u76f8\u7576\u5927\u7684\u98a8\u96aa\u548c\u56b4\u91cd\u7684\u526f\u4f5c\u7528\uff0c\u6df1\u6df1\u5f71\u97ff\u75c5\u60a3\u7684\u751f\u6d3b\u54c1\u8cea\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li><strong>\u9aa8\u9ad3\u6291\u5236\uff0878% \u767c\u751f\uff09\uff1a<\/strong> \u983b\u7e41\u7684\u5316\u7642\u9031\u671f\u6703\u9020\u6210\u986f\u8457\u7684\u9aa8\u9ad3\u6291\u5236\uff0c\u53ef\u80fd\u5c0e\u81f4\u8ca7\u8840\u3001\u4e2d\u6027\u7c92\u8840\u7403\u6e1b\u5c11\u548c\u8840\u5c0f\u677f\u6e1b\u5c11\uff0c\u5927\u5927\u589e\u52a0\u611f\u67d3\u548c\u51fa\u8840\u7684\u98a8\u96aa\u3002<\/li>\n<li><strong>\u5fc3\u81df\u6bd2\u6027\uff0823% \u767c\u751f\uff09\uff1a<\/strong> \u591a\u67d4\u6bd4\u661f (doxorubicin) \u7b49\u5316\u7642\u85e5\u7269\u53ef\u80fd\u6703\u9020\u6210\u5f71\u97ff\u751f\u547d\u7684\u5fc3\u8840\u7ba1\u4f75\u767c\u75c7\uff0c\u5e7e\u4e4e\u6bcf\u56db\u500b\u4eba\u4e2d\u5c31\u6709\u4e00\u4eba\u6703\u51fa\u73fe\u5fc3\u81df\u529f\u80fd\u969c\u7919\u3002\u9019\u5927\u5927\u9650\u5236\u4e86\u9577\u671f\u6cbb\u7642\u7684\u5316\u7642\u5291\u91cf\u548c\u983b\u7387\uff0c\u751a\u81f3\u53ef\u80fd\u59a8\u7919\u672a\u4f86\u7684\u6cbb\u7642\u7642\u7a0b\u3002<\/li>\n<li><strong>\u56b4\u91cd\u80c3\u8178\u9053\u5f71\u97ff\uff1a<\/strong> \u5316\u7642\u85e5\u7269\u901a\u5e38\u6703\u9020\u6210\u5ee3\u6cdb\u7684\u80c3\u8178\u9053\u4f75\u767c\u75c7\uff0c\u5305\u62ec\u5641\u5fc3\u3001\u5614\u5410\u3001\u9ecf\u819c\u767c\u708e\u4ee5\u53ca\u75c5\u60a3\u98df\u617e\u5927\u6e1b\u3002\u672a\u7d93\u8655\u7406\u7684\u80c3\u8178\u9053\u75c7\u72c0\u6703\u52a0\u91cd\u9ad4\u91cd\u5927\u5e45\u4e0b\u964d\u548c\u71df\u990a\u4e0d\u8db3\u7684\u60c5\u6cc1\uff0c\u56e0\u800c\u5728\u6cbb\u7642\u7684\u95dc\u9375\u6642\u671f\u56b4\u91cd\u640d\u5bb3\u75c5\u60a3\u7684\u9ad4\u529b\u548c\u514d\u75ab\u529f\u80fd\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u653e\u5c04\u6cbb\u7642\uff1a\u901a\u5e38\u662f\u4e00\u628a\u96d9\u5203\u528d<\/h3>\n<p class=\"p-cancertype\">\u5118\u7ba1\u653e\u5c04\u7dda\u6cbb\u7642\u5728\u6cbb\u7642\u5c40\u90e8\u75be\u75c5\u65b9\u9762\u6709\u5f88\u9ad8\u7684\u4f7f\u7528\u7387\uff0c\u4f46\u5b83\u5c0d\u65bc\u816b\u7624\u7684\u6cbb\u7642\u537b\u6c92\u6709\u4efb\u4f55\u5e6b\u52a9\u3002 <strong>\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/strong>......\uff0c\u526f\u4f5c\u7528\u983b\u7e41\u4e14\u4f75\u767c\u75c7\u56b4\u91cd\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li><strong>\u7d44\u7e54\u640d\u50b7\u548c\u7e96\u7dad\u5316\uff1a<\/strong> \u816b\u7624\u90e8\u4f4d\u5468\u570d\u7684\u5065\u5eb7\u7d44\u7e54\uff0c\u5c24\u5176\u662f DSRCT \u7684\u8179\u90e8\u6216\u9aa8\u76c6\u5340\u57df\uff0c\u5f88\u5bb9\u6613\u53d7\u5230\u6709\u5bb3\u8f3b\u5c04\u7167\u5c04\uff0c\u5c0e\u81f4\u5065\u5eb7\u5668\u5b98\u51fa\u73fe\u4e0d\u53ef\u9006\u7684\u7e96\u7dad\u5316\uff0c\u9032\u800c\u9020\u6210\u5668\u5b98\u529f\u80fd\u969c\u7919\u3002<\/li>\n<li><strong>\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u98a8\u96aa (300% \u589e\u52a0\u98a8\u96aa)\uff1a<\/strong> \u6b63\u5982\u91ab\u5b78\u6587\u737b\u6240\u5ee3\u6cdb\u8a18\u8f09\u7684\uff0c\u9ad8\u5291\u91cf\u8f3b\u5c04\u6703\u986f\u8457\u589e\u52a0\u672a\u4f86\u7f79\u60a3\u764c\u75c7\u7684\u98a8\u96aa\u30022023 \u5e74\u300a\u7f8e\u570b\u816b\u7624\u5b78\u6703\u6703\u520a\u300b\uff08JAMA Oncology\uff09\u7684\u4e00\u9805\u958b\u5275\u6027\u7814\u7a76\u5f37\u8abf\uff0c\u66b4\u9732\u65bc\u9ad8\u5291\u91cf\u8f3b\u5c04\u7684 DSRCT \u5016\u5b58\u8005\u9577\u671f\u7f79\u60a3\u5f8c\u7e8c\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa\u589e\u52a0\u4e09\u500d (300%)\u3002<\/li>\n<li><strong>\u75b2\u52de\u548c\u529f\u80fd\u9650\u5236\uff1a<\/strong> \u8f3b\u5c04\u5f8c\u7684\u6162\u6027\u75b2\u52de\u6703\u56b4\u91cd\u964d\u4f4e\u75c5\u60a3\u7684\u6d3b\u52d5\u91cf\uff0c\u56b4\u91cd\u5e72\u64fe\u65e5\u5e38\u751f\u6d3b\u3001\u5b78\u696d\u6216\u8077\u696d\u6d3b\u52d5\uff0c\u4ee5\u53ca\u6574\u9ad4\u7684\u5fa9\u5065\u548c\u5eb7\u5fa9\u76ee\u6a19\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u624b\u8853\u65b9\u6cd5\uff1a\u53d7\u5230\u56b4\u91cd\u98a8\u96aa\u548c\u5fa9\u767c\u7387\u7684\u9650\u5236<\/h3>\n<p class=\"p-cancertype\">\u7a4d\u6975\u7684\u624b\u8853\u5207\u9664\u88ab\u8a8d\u70ba\u662f\u6cbb\u7642\u5c40\u90e8\u816b\u7624\u7684\u6700\u4f73\u65b9\u6cd5\uff0c\u4f46\u537b\u6709\u8a31\u591a\u56fa\u6709\u7684\u98a8\u96aa\uff0c\u800c\u4e14\u5fa9\u767c\u63a7\u5236\u7387\u4e5f\u4e0d\u4ee4\u4eba\u6eff\u610f\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li><strong>\u611f\u67d3\u8207\u624b\u8853\u6b7b\u4ea1\u7387\uff1a<\/strong> DSRCT \u76f8\u95dc\u7684\u8907\u96dc\u624b\u8853\u901a\u5e38\u6d89\u53ca\u5ee3\u6cdb\u7684\u8179\u90e8\u6216\u9aa8\u76c6\u5207\u9664\uff0c\u6703\u589e\u52a0\u611f\u67d3\u7387\u3001\u51fa\u8840\u3001\u624b\u8853\u5f8c\u4f75\u767c\u75c7\uff0c\u5076\u723e\u9084\u6703\u9020\u6210\u56b4\u91cd\u7684\u767c\u75c5\u6216\u6b7b\u4ea1\u3002<\/li>\n<li><strong>\u816b\u7624\u5fa9\u767c\u7387\u9ad8\uff1a<\/strong> \u5118\u7ba1\u7a4d\u6975\u7684\u5207\u9664\u624b\u8853\u80fd\u6709\u6548\u53bb\u9664\u53ef\u898b\u7684\u816b\u7624\uff0c\u4f46\u5fa9\u767c\u7387\u4ecd\u7136\u9ad8\u5f97\u4ee4\u4eba\u64d4\u6182\u3002\u4e9e\u6d32\u5730\u5340\u7684\u7814\u7a76\u6301\u7e8c\u986f\u793a\u624b\u8853\u5f8c 24 \u500b\u6708\u5167\u7684\u5fa9\u767c\u7387\u8d85\u904e 60%\uff0c\u5f37\u8abf\u624b\u8853\u4f5c\u70ba\u55ae\u7368\u6cbb\u7642\u7684\u9577\u671f\u7642\u6548\u6709\u9650\u3002<\/li>\n<li><strong>\u624b\u8853\u5f8c\u7684\u529f\u80fd\u969c\u7919\uff1a<\/strong> \u624b\u8853\u65b9\u5f0f\u53ef\u80fd\u6703\u9020\u6210\u986f\u8457\u7684\u89e3\u5256\u7d50\u69cb\u6539\u8b8a\u3001\u80c3\u8178\u9053\u7e2e\u77ed\u548c\u529f\u80fd\u9650\u5236\uff0c\u56b4\u91cd\u640d\u5bb3\u75c5\u60a3\u7684\u798f\u7949\uff0c\u4e26\u56b4\u91cd\u5f71\u97ff\u9577\u671f\u5eb7\u5fa9\u548c\u7368\u7acb\u6027\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">\u665a\u671f\u548c\u8f49\u79fb\u6027\u75be\u75c5\u7642\u6548\u4f4e\u4e14\u9810\u5f8c\u6709\u9650<\/h3>\n<p class=\"p-cancertype\">\u4e0d\u5e78\u7684\u662f\uff0c\u50b3\u7d71\u7642\u6cd5\u7684\u7642\u6548\u4e00\u65e6\u986f\u8457\u964d\u4f4e\u3002 <strong>\u812b\u5c51\u6027\u5c0f\u5713\u7d30\u80de\u7624 (DSRCT)<\/strong> \u9054\u5230\u665a\u671f\u6216\u8f49\u79fb\u968e\u6bb5\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li><strong>\u5ba2\u89c0\u56de\u61c9\u7387\u4f4e\u65bc 21%\uff1a<\/strong> \u665a\u671f\u548c\u8f49\u79fb\u75c5\u4f8b\u5831\u544a\u8207\u50b3\u7d71\u5316\u7642\u65b9\u6848\u76f8\u95dc\u7684\u5ba2\u89c0\u53cd\u61c9\u7387\u4f4e\u5f97\u9a5a\u4eba\uff0c\u53ea\u6709\u4e0d\u5230\u4e94\u5206\u4e4b\u4e00\u7684\u60a3\u8005\u51fa\u73fe\u53ef\u6e2c\u91cf\u7684\u816b\u7624\u7e2e\u5c0f\u6216\u75c5\u60c5\u7a69\u5b9a\u3002<\/li>\n<li><strong>\u75be\u75c5\u5feb\u901f\u767c\u5c55\uff1a<\/strong> \u665a\u671f\u7684 DSRCT \u901a\u5e38\u5c0d\u5316\u7642\u548c\u653e\u5c04\u6cbb\u7642\u6709\u76f8\u7576\u5927\u7684\u62b5\u6297\u529b\uff0c\u5118\u7ba1\u63a1\u53d6\u7a4d\u6975\u7684\u6cbb\u7642\u65b9\u5f0f\uff0c\u75c5\u60c5\u4ecd\u7d93\u5e38\u60e1\u5316\uff0c\u56e0\u6b64\u5927\u5e45\u964d\u4f4e\u9810\u5f8c\u8207\u6574\u9ad4\u5b58\u6d3b\u7387\u3002<\/li>\n<li><strong>\u7121\u6548\u7684\u6df7\u5408\u7642\u6cd5\uff1a<\/strong> \u50b3\u7d71\u7684\u6cbb\u7642\u7d44\u5408\uff0c\u5373\u4f7f\u662f\u591a\u6a21\u5f0f\u65b9\u6cd5\uff0c\u4e5f\u7121\u6cd5\u5927\u5e45\u5ef6\u9577 IV \u671f DSRCT \u60a3\u8005\u7684\u4e2d\u4f4d\u751f\u5b58\u6642\u9593\u3002\u5f8c\u7e8c\u6cbb\u7642\u5931\u6557\u7684\u6848\u4f8b\u5c62\u898b\u4e0d\u9bae\uff0c\u9019\u5f37\u8abf\u4e86\u665a\u671f\u6cbb\u7642\u5c1a\u672a\u6eff\u8db3\u7684\u9700\u6c42\u548c\u5de8\u5927\u7684\u6cbb\u7642\u9650\u5236\u3002<\/li>\n<\/ul>\n<h3 class=\"h3-cancertype\">DSRCT \u7684\u50b3\u7d71\u6cbb\u7642\u9650\u5236\u6bd4\u8f03\u8868<\/h3>\n<table class=\"p-cancertype\">\n<thead>\n<tr>\n<th>\u764c\u75c7\u6cbb\u7642<\/th>\n<th>\u4e3b\u8981\u7f3a\u9ede<\/th>\n<th>\u5f71\u97ff\u7a0b\u5ea6<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>\u5316\u5b78\u6cbb\u7642<\/td>\n<td>\n<ul>\n<li>\u9aa8\u9ad3\u6291\u5236 (78%)<\/li>\n<li>\u5fc3\u81df\u6bd2\u6027 (23%)<\/li>\n<li>\u56b4\u91cd\u7684\u80c3\u8178\u9053\u5f71\u97ff<\/li>\n<\/ul>\n<\/td>\n<td>\u9ad8<\/td>\n<\/tr>\n<tr>\n<td>\u653e\u5c04\u6cbb\u7642<\/td>\n<td>\n<ul>\n<li>\u7d44\u7e54\u7e96\u7dad\u5316\u548c\u640d\u50b7<\/li>\n<li>300% \u589e\u52a0\u7e7c\u767c\u6027\u60e1\u6027\u816b\u7624\u7684\u98a8\u96aa<\/li>\n<li>\u56b4\u91cd\u75b2\u52de<\/li>\n<\/ul>\n<\/td>\n<td>\u9ad8<\/td>\n<\/tr>\n<tr>\n<td>\u624b\u8853<\/td>\n<td>\n<ul>\n<li>\u9ad8\u611f\u67d3\u98a8\u96aa<\/li>\n<li>\u9ad8\u5fa9\u767c\u7387 (&gt;60%)<\/li>\n<li>\u8853\u5f8c\u529f\u80fd\u969c\u7919<\/li>\n<\/ul>\n<\/td>\n<td>\u4e2d\u5ea6\u81f3\u9ad8\u5ea6<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h3 class=\"h3-cancertype\">\u4f7f DSRCT \u6cbb\u7642\u8907\u96dc\u5316\u7684\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236<\/h3>\n<p class=\"p-cancertype\">\u50b3\u7d71\u6cbb\u7642\u65b9\u6848\u6210\u6548\u4e0d\u5f70\u7684\u95dc\u9375\u539f\u56e0\uff0c\u5728\u65bc DSRCT \u764c\u7d30\u80de\u672c\u8eab\u6240\u5c55\u73fe\u7684\u65b0\u9673\u4ee3\u8b1d\u62b5\u6297\u6a5f\u5236\u3002<\/p>\n<ul class=\"p-cancertype\">\n<li><strong>\u589e\u5f37 DNA \u4fee\u5fa9\u9175\u7d20\u6d3b\u6027 (400% \u589e\u52a0)\uff1a<\/strong> \u5148\u9032\u7684\u57fa\u56e0\u7d44\u5206\u6790\u986f\u793a\uff0cDSRCT \u7d30\u80de\u7684 DNase \u542b\u91cf\u986f\u8457\u5347\u9ad8\uff0c\u53ef\u5728\u5316\u7642\u6216\u653e\u5c04\u6cbb\u7642\u5f8c\u5feb\u901f\u4fee\u5fa9 DNA\uff0c\u8b93\u816b\u7624\u7d30\u80de\u5728\u6cbb\u7642\u5f15\u8d77\u7684\u640d\u50b7\u4e2d\u5b58\u6d3b\u4e0b\u4f86\u3002<\/li>\n<li><strong>\u8461\u8404\u7cd6\u4ee3\u8b1d\u5347\u9ad8\uff1a<\/strong> DSRCT \u764c\u7d30\u80de\u5c0d\u8461\u8404\u7cd6\u7684\u5229\u7528\u7387\u6bd4\u6b63\u5e38\u7d44\u7e54\u7d30\u80de\u9ad8\u7d04 200 \u500d\uff0c\u53cd\u6620\u51fa Warburg \u4ee3\u8b1d\u7684\u8106\u5f31\u6027\u3002\u9019\u7a2e\u589e\u5f37\u7684\u8461\u8404\u7cd6\u4f9d\u8cf4\u6027\u6709\u52a9\u65bc\u6297\u6027\u901a\u8def\uff0c\u5e6b\u52a9\u816b\u7624\u7d30\u80de\u5728\u7d30\u80de\u6bd2\u6027\u5e72\u9810\u5f8c\u80fd\u5feb\u901f\u6062\u5fa9\u3002<\/li>\n<li><strong>\u589e\u52a0 Glutamine \u4f9d\u8cf4\u6027\uff1a<\/strong> DSRCT \u7d30\u80de\u986f\u793a\u8c37\u6c28\u9170\u80fa\u766e\u589e\u52a0\uff0c\u5728\u4fb5\u7565\u6027\u6cbb\u7642\u671f\u9593\uff0c\u5118\u7ba1\u71df\u990a\u88ab\u525d\u596a\u7684\u60c5\u6cc1\u4e0b\uff0c\u4ecd\u80fd\u589e\u5f37\u816b\u7624\u7d30\u80de\u7684\u5b58\u6d3b\u8207\u589e\u6b96\uff0c\u56e0\u800c\u5927\u5927\u589e\u52a0\u6cbb\u7642\u7684\u8010\u53d7\u6027\u3002<\/li>\n<\/ul>\n<p class=\"p-cancertype\">\u9451\u65bc\u9019\u4e9b\u91cd\u5927\u7684\u9650\u5236\uff0c\u50b3\u7d71\u7684\u6cbb\u7642\u65b9\u6cd5\u4e26\u4e0d\u8db3\u4ee5\u89e3\u6c7a DSRCT \u7684\u4fb5\u8972\u6027\u548c\u8907\u96dc\u6027\uff0c\u9019\u4e00\u9ede\u4ecd\u7136\u975e\u5e38\u660e\u986f\u3002\u76ee\u524d\u7684\u7814\u7a76\u91cd\u9ede\u8207\u65b0\u578b\u7642\u6cd5\u5fc5\u9808\u6301\u7e8c\u7dca\u5bc6\u767c\u5c55\uff0c\u624d\u80fd\u6709\u6548\u514b\u670d\u9019\u4e9b\u56fa\u6709\u7684\u6cbb\u7642\u969c\u7919\uff0c\u4e26\u70ba\u5ef6\u9577\u5b58\u6d3b\u671f\u8207\u6539\u5584\u751f\u6d3b\u54c1\u8cea\u5e36\u4f86\u771f\u6b63\u7684\u5e0c\u671b\u3002<\/p>","protected":false},"excerpt":{"rendered":"<p>What Is Desmoplastic Small Round Cell Tumor (DSRCT)? Desmoplastic Small Round Cell Tumor (DSRCT) is a rare, aggressive form of soft-tissue sarcoma primarily affecting adolescents and young adults. Characterized by small, round malignant cells surrounded by dense fibrous tissue (desmoplasia), DSRCT commonly arises in the abdomen, pelvis, or peritoneal lining. Understanding Desmoplastic Small Round Cell [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":7916,"parent":0,"menu_order":0,"template":"","class_list":["post-7965","cancer_type","type-cancer_type","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type\/7965","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/cancer_type"}],"about":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/types\/cancer_type"}],"author":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/users\/3"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media\/7916"}],"wp:attachment":[{"href":"https:\/\/allcancer.com\/hk\/wp-json\/wp\/v2\/media?parent=7965"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}